Phenolic composition and antiparasitic activity of plants from the Brazilian Northeast ‘‘Cerrado”
Joint Authors
Ju´nior, Joao Tavares Calixto
Morais, Selene Maia de
Gomez, Celeste Vega
Molas, Cathia Coronel
Rolon, Miriam
Boligon, Aline Augusti
Oliveira, Cı´cera Datiane de Morais
Tintino, Saulo Relison
Coutinho, Henrique Douglas Melo
Athayde, Margareth Linde
Source
Saudi Journal of Biological Sciences
Issue
Vol. 23, Issue 3 (31 May. 2016), pp.434-440, 7 p.
Publisher
Publication Date
2016-05-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Abstract EN
This work describes the antiparasitic and cytotoxic activities of three plant species from the Cerrado biome, Northeastern Brazil.
Significant antiparasitic inhibition was observed against Trypanosoma cruzi (63.86%), Leishmania brasiliensis (92.20%) and Leishmania infantum (95.23%) when using ethanol extract from leaves of Guazuma ulmifolia Lam.
(Malvaceae), at a concentration of 500 lg/mL.
However, low levels of inhibition were observed when assessing leishmanicidal and trypanocidal (Clone CL-B5) activities of crude ethanol extracts from leaves and bast tissue of Luehea paniculata (Malvaceae) and leaves and bark of Prockia crucis (Salicaceae) at a concentration of 500 lg/mL.
The extracts revealed the presence of phenolic acids such as gallic acid, chlorogenic acid, caffeic acid and rosmarinic acid, as well as flavonoids such as rutin, luteolin, apigenin and quercetin – the latter detected only in G.
ulmifolia.
G.
ulmifolia extract displayed higher leishmanicidal activity probably due to the presence of quercetin, a potent known leishmanicidal compound.
A cytotoxicity test indicated values over 50% at the highest concentration (1000 lg/mL) for all natural products
American Psychological Association (APA)
Ju´nior, Joao Tavares Calixto& Morais, Selene Maia de& Gomez, Celeste Vega& Molas, Cathia Coronel& Rolon, Miriam& Boligon, Aline Augusti…[et al.]. 2016. Phenolic composition and antiparasitic activity of plants from the Brazilian Northeast ‘‘Cerrado”. Saudi Journal of Biological Sciences،Vol. 23, no. 3, pp.434-440.
https://search.emarefa.net/detail/BIM-689446
Modern Language Association (MLA)
Ju´nior, Joao Tavares Calixto…[et al.]. Phenolic composition and antiparasitic activity of plants from the Brazilian Northeast ‘‘Cerrado”. Saudi Journal of Biological Sciences Vol. 23, no. 3 (May. 2016), pp.434-440.
https://search.emarefa.net/detail/BIM-689446
American Medical Association (AMA)
Ju´nior, Joao Tavares Calixto& Morais, Selene Maia de& Gomez, Celeste Vega& Molas, Cathia Coronel& Rolon, Miriam& Boligon, Aline Augusti…[et al.]. Phenolic composition and antiparasitic activity of plants from the Brazilian Northeast ‘‘Cerrado”. Saudi Journal of Biological Sciences. 2016. Vol. 23, no. 3, pp.434-440.
https://search.emarefa.net/detail/BIM-689446
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 439-440
Record ID
BIM-689446