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CART peptides and drugs of abuse : a review of recent progress
Author
Source
Journal of Drug and Alcohol Research
Issue
Vol. 5, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Publication Date
2016-12-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Earlier studies suggesting an involvement of cocaine and amphetamine regulated transcript peptide (CARTp) in the actions of drugs of abuse are confirmed in the most recent publications.
This seems especially true for the psychostimulants where CARTp in the nucleus accumbens inhibits or regulates the actions of these drugs; the regulation is lost after repeated drug use which may be an important mechanism in addiction.
The other drugs, including nicotine, alcohol, opiates, and perhaps caffeine can affect CARTp or CART mRNA levels.
While the exact mechanism is not always clear, the hope is that these findings may provide some insight for the development of medications.
While binding studies indicate the existence of specific G-protein coupled receptors (GPCR) receptors for CARTp,major work to be done is the cloning of these receptors
American Psychological Association (APA)
Kuhar, Michael J.. 2016. CART peptides and drugs of abuse : a review of recent progress. Journal of Drug and Alcohol Research،Vol. 5, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-690783
Modern Language Association (MLA)
Kuhar, Michael J.. CART peptides and drugs of abuse : a review of recent progress. Journal of Drug and Alcohol Research Vol. 5 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-690783
American Medical Association (AMA)
Kuhar, Michael J.. CART peptides and drugs of abuse : a review of recent progress. Journal of Drug and Alcohol Research. 2016. Vol. 5, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-690783
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 5-6
Record ID
BIM-690783