Preprative radiochemotherapy in locally advanced rectal cancer
Joint Authors
Ismail, Abd al-Salam A.
Kosba, Yahya A.
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 13, Issue 2 (30 Jun. 2001), pp.101-108, 8 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2001-06-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
Combined modality has proven efficacy in many malignant tumors (head and neck, cervix) with the advantage of organ preservation.
Therefore we studied 15 patients with locally advanced rectal cancer (T3-4, Nx, M0).
Patients received 45-50 Gy whole pelvic irradiation concomitant with 20 mg / m2 leucovorin (30 minute IV infusion) and 5-fluorouracil 370 mg/m2 (1 hour IV infusion) days 1-5 and repeated days 29-34 through the course of radiotherapy (RT).
Surgery performed 4-6 weeks from the end of RT.
Ten out of fifteen patients showed clinical down-staging.
There was no enhancement of the toxicity and all the patients had unremarkable postoperative course.
In conclusion radio chemotherapy is feasible, safe and effective with good down staging in locally advanced rectal can-car.
American Psychological Association (APA)
Ismail, Abd al-Salam A.& Kosba, Yahya A.. 2001. Preprative radiochemotherapy in locally advanced rectal cancer. Journal of the Egyptian National Cancer Institute،Vol. 13, no. 2, pp.101-108.
https://search.emarefa.net/detail/BIM-69138
Modern Language Association (MLA)
Ismail, Abd al-Salam A.& Kosba, Yahya A.. Preprative radiochemotherapy in locally advanced rectal cancer. Journal of the Egyptian National Cancer Institute Vol. 13, no. 2 (Jun. 2001), pp.101-108.
https://search.emarefa.net/detail/BIM-69138
American Medical Association (AMA)
Ismail, Abd al-Salam A.& Kosba, Yahya A.. Preprative radiochemotherapy in locally advanced rectal cancer. Journal of the Egyptian National Cancer Institute. 2001. Vol. 13, no. 2, pp.101-108.
https://search.emarefa.net/detail/BIM-69138
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 106-108
Record ID
BIM-69138