Effect of phenolic compound extract of Artemisia herba alba on the ultra-structural and BCl2 expression

Abstract EN

The results of the IHC showed there was positive expression for bcl2 in the control group with high score (++) high and this expression will decrease with the increase of the dose of the PC extract in the treated group .And the results of the ultrastructural examination by using TEM showed there was increase in the N/C ratio, well developed ER, increase number of variably sized mitochondria in the control group while the treated group revealed there was many vacuoles in the cytoplasm , plasma membrane blebbing and formation the apoptotic bodies.

From our study we concluded that there was clear effect on the ultrastructural after using PC as anti- tumor.