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PVC polymeric membranes coated graphite electrodes based on molecularly imprinted polymers for the selective determination of glibenclamide
Other Title(s)
أغشية بوليمرية لمتعدد كلوريد الفاينيل على أقطاب كرافيت معتمدة على بوليمرات الطبعة الجزيئية للتقدير الانتقائي لعقار (الكلبينكلامايد)
Joint Authors
Yasin, Hamsah Munim
Abd Allah, Najwa Ishaq
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 29, Issue 1 (30 Apr. 2016), pp.133-149, 17 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2016-04-30
Country of Publication
Iraq
No. of Pages
17
Main Subjects
Topics
Abstract EN
-Graphite coated electrodes (GCE) based on molecularly imprinted polymers were fabricated for the selective potentiometric determination of Glibenclamide (Glb).
The molecularly imprinted (MIP) and nonimprinted (NIP) polymers were synthesized by radical bulk polymerization using (Glb.) as a template, acrylic acid (AA) and acrylamide (AAm) as monomers, ethylene glycol dimethacrylate (EGDMA) as a cross-linker and benzoyl peroxide (BPO) as an initiator.
The imprinted membranes and the non-imprinted membranes were prepared using dioctyl phthalate (DOP) and Dibutylphthalate (DBP) as plasticizers in PVC matrix.
The membranes were coated on graphite electrodes.
The MIP electrodes using (AA) and (AAm) showed a near nernstian response with slopes of -51.5±0.5and - 57.8±0.1mV/decade, correlation coefficient (r2) 0.9762 and 0.9992, a linear response for a concentration range of (1.0×10-4- 1.0×10-2) M and (1.0×10-5- 1.0×10-3) M and detection limit of 1.0×10-4M and 1.0×10-5M respectively.
The response time of the prepared electrodes was less than 30 seconds.
The electrode responses were stable in a pH range (2-4).
The electrodes could be successfully used within (1and 6) weeks respectively without any drift.
The sensors exhibited good selectivity over a wide range of interference.
The most effective electrode was used to determine the concentration of (Glb.) in some pharmaceutical formulations.
American Psychological Association (APA)
Yasin, Hamsah Munim& Abd Allah, Najwa Ishaq. 2016. PVC polymeric membranes coated graphite electrodes based on molecularly imprinted polymers for the selective determination of glibenclamide. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 29, no. 1, pp.133-149.
https://search.emarefa.net/detail/BIM-692497
Modern Language Association (MLA)
Yasin, Hamsah Munim& Abd Allah, Najwa Ishaq. PVC polymeric membranes coated graphite electrodes based on molecularly imprinted polymers for the selective determination of glibenclamide. Ibn al-Haitham Journal for Pure and Applied Science Vol. 29, no. 1 (2016), pp.133-149.
https://search.emarefa.net/detail/BIM-692497
American Medical Association (AMA)
Yasin, Hamsah Munim& Abd Allah, Najwa Ishaq. PVC polymeric membranes coated graphite electrodes based on molecularly imprinted polymers for the selective determination of glibenclamide. Ibn al-Haitham Journal for Pure and Applied Science. 2016. Vol. 29, no. 1, pp.133-149.
https://search.emarefa.net/detail/BIM-692497
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 141-148
Record ID
BIM-692497