The first experience of sequential liver-kidney transplantation for the treatment of primary hyperoxaluria type-1 in Iran as a developing country
Joint Authors
Nadiri, Ghulam Husayn
Tabassomi, Fayruzih
Latif, Amir Husayn
Ganji, Muhammad Rida
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 4 (31 Aug. 2016), pp.791-794, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-08-31
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Liver
- Tests
- Case studies
- Kidneys
- Diseases
- Penal functions
- Therapeutics
- Hemodialysis
- Iran
- Organ transplantation
- Hyperoxaluria
- Genetic aspects
- Kidney failure
- Biopsy
- Kidney glomerulus
- Diagnosis
- Calculi(Pathology)
Abstract EN
Primary hyperoxaluria Type-1 (PH-1) is caused by a deficiency of alanineglyoxylate aminotransferase manifesting as urolithiasis, nephrocalcinosis, and end-stage renal disease (ESRD).
Among treatment options, best outcomes have been achieved by sequential liverkidney transplantation (Seq-LKT).
Herein, we report a patient with PH-1 and ESRD who underwent Seq-LKT in Iran.
Criteria for diagnosis included a history of recurring calcium oxalate renal stones and elevated urine oxalate level combined with liver biopsy and absent enzymatic activity at the age of 13 years.
Conservative treatment including pyridoxine, potassium citrate solution, high fluid intake, and hemodialysis was administered initially.
Liver transplantation was performed at the age of 17 years from a deceased donor followed 4½ months later by a livingunrelated donor kidney transplantation.
After two years of follow-up, the patient experienced no complications and had normal liver and renal function.
This is the first successful experience of Seq-LKT in the treatment of PH-1 in Iran as a developing country with limited access to equipment and medications.
American Psychological Association (APA)
Nadiri, Ghulam Husayn& Tabassomi, Fayruzih& Latif, Amir Husayn& Ganji, Muhammad Rida. 2016. The first experience of sequential liver-kidney transplantation for the treatment of primary hyperoxaluria type-1 in Iran as a developing country. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 4, pp.791-794.
https://search.emarefa.net/detail/BIM-693148
Modern Language Association (MLA)
Tabassomi, Fayruzih…[et al.]. The first experience of sequential liver-kidney transplantation for the treatment of primary hyperoxaluria type-1 in Iran as a developing country. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 4 (Jul. / Aug. 2016), pp.791-794.
https://search.emarefa.net/detail/BIM-693148
American Medical Association (AMA)
Nadiri, Ghulam Husayn& Tabassomi, Fayruzih& Latif, Amir Husayn& Ganji, Muhammad Rida. The first experience of sequential liver-kidney transplantation for the treatment of primary hyperoxaluria type-1 in Iran as a developing country. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 4, pp.791-794.
https://search.emarefa.net/detail/BIM-693148
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 794
Record ID
BIM-693148