Minimal change disease : a case report of an unusual relationship
Joint Authors
Black, Robert M.
Idris, Fahd
Leb, Laszlo
Rennke, Helmut
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 4 (31 Aug. 2016), pp.816-820, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-08-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
- Case studies
- Kidneys
- Diseases
- Wounds and injuries
- Kidney failure
- Nephrotic syndrome
- Biopsy
- Lymphoproliferative disorders
- Glomerulonephritis
Abstract EN
Kidney injury associated with lymphoproliferative disorders is rare, and the exact pathogenetic mechanisms behind it are still poorly understood.
Glomerular involvement presenting as a nephrotic syndrome has been reported, usually secondary to membranoproliferative glomerulonephritis.
We report a case of a 63-year-old male who presented with bilateral leg swelling due to nephrotic syndrome and acute kidney injury.
A kidney biopsy showed minimal change disease with light chain deposition; however, no circulating light chains were present.
This prompted a bone marrow biopsy, which showed chronic lymphocytic leukemia (CLL) with deposition of the same kappa monoclonal light chains.
Three cycles of rituximab and methylprednisolone resulted in remission of both CLL and nephrotic syndrome, without recurrence during a three-year follow-up.
American Psychological Association (APA)
Idris, Fahd& Black, Robert M.& Leb, Laszlo& Rennke, Helmut. 2016. Minimal change disease : a case report of an unusual relationship. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 4, pp.816-820.
https://search.emarefa.net/detail/BIM-693170
Modern Language Association (MLA)
Idris, Fahd…[et al.]. Minimal change disease : a case report of an unusual relationship. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 4 (Jul. / Aug. 2016), pp.816-820.
https://search.emarefa.net/detail/BIM-693170
American Medical Association (AMA)
Idris, Fahd& Black, Robert M.& Leb, Laszlo& Rennke, Helmut. Minimal change disease : a case report of an unusual relationship. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 4, pp.816-820.
https://search.emarefa.net/detail/BIM-693170
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 820
Record ID
BIM-693170