Correlation of calcium with lipid profile in patients with chronic renal failure on regular hemodialysis

Abstract EN

Objective: Chronic renal failure (CRF) is associated with premature atherosclerosis and increased incidence of cardiovascular morbidity and mortality.

This study aims to evaluate lipid profile parameters among CRF patients on regular hemodialysis (HD), and to identify the relationship between these parameters and serum calcium with risk of atherosclerosis in these patients.

Methods: A cross-sectional study was conducted from April 2013 to June 2014 in dialysis unit in Imamein Kadhmian Medical City.

A total of 100 patients with CRF on regular HD were involved in this study.

A matching group of a similar number of healthy persons were included as controls.

Measurement of serum calcium and lipid profile was performed to all patients Results: Serum lipid profile was not significantly altered in patients when compared with controls (p>0.05), apart from a significant increase (p<0.05) in Atherogenic index in patients compared to controls.

A significant positive correlation was found between serum calcium and atherogenic index in HD group (r=0.9, p-value <0.05); but not in the control group.

Conclusions: Alterations in the calcium status correlates with atherogenic index which indirectly related to atherosclerotic process in patients on chronic HD.