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Synthesis and biological effectiveness of some new Azo compounds as derivatives of nitrogen bases
Other Title(s)
تحضير و دراسة الفعالية الحيوية لبعض مركبات الآزو الجديدة كمشتقات للقواعد النايتروجينية
Joint Authors
Zaydan, Nur Khalid
Muhammad, Wisam Mahmud
Source
Issue
Vol. 13, Issue 2 (30 Jun. 2016), pp.368-375, 8 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
In this study the new azo compounds (3compounds) for nitrogen bases (Adenine and Cytosine) are synthesized through two reaction steps (formation of diazonium salt and coupling reaction).
The compounds have been characterized by FTIR, melting point, and ultra-violate (UV) spectra.
All synthesized compounds have been estimated in vitro for their antimicrobial activities against two species of bacteria(E.coli, S.aureus)and one kind of fungi ( Aspergillus flavus) .The results show that these compounds have very good antibacterial and antifungal activities especially compounds 1 and 3.To study the effect of these compounds were making some physiological tests on rats are made ,the results of hematological study showed decreasing level of total hemoglobin concentration in all treatment groups specially in group (1).The values of Packed in cell volume (P.C.V) are within normal blood range of rats .
Total leucocytes count (W.B.C) decrease in all groups
American Psychological Association (APA)
Zaydan, Nur Khalid& Muhammad, Wisam Mahmud. 2016. Synthesis and biological effectiveness of some new Azo compounds as derivatives of nitrogen bases. Baghdad Science Journal،Vol. 13, no. 2, pp.368-375.
https://search.emarefa.net/detail/BIM-695062
Modern Language Association (MLA)
Zaydan, Nur Khalid& Muhammad, Wisam Mahmud. Synthesis and biological effectiveness of some new Azo compounds as derivatives of nitrogen bases. Baghdad Science Journal Vol. 13, no. 2 (2016), pp.368-375.
https://search.emarefa.net/detail/BIM-695062
American Medical Association (AMA)
Zaydan, Nur Khalid& Muhammad, Wisam Mahmud. Synthesis and biological effectiveness of some new Azo compounds as derivatives of nitrogen bases. Baghdad Science Journal. 2016. Vol. 13, no. 2, pp.368-375.
https://search.emarefa.net/detail/BIM-695062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 373-375
Record ID
BIM-695062