Determination concentrations of serum ceruloplasmin, copper, enzymes activity and liver copper concentration of different ages of Karadi sheep at in Sulaimani Province

Abstract EN

The objectives of this study was to measure the Concentrations of serum ceruloplasmin, Copper, enzymes activity and liver copper in Karadi sheep at different ages.

The study was carried out on eighty Karadi sheep(47 male and 33 female) were used and taken from the slaughterhouse, the province of Sulaimani during period November 2009 to June 2010.

Blood samples (10 ml) were collected from each animal before slaughtering and the serum were separated.

Results indicated that the overall mean serum ceruloplasmin , serum copper and liver copper concentration l were 112.55 ± 13.047 mg/dl, 110.66 ± 4.56 ug\dl and 129.43 ± 4.52 ug\dl, respectively.

Serum ALT and AST activity were 30.18 ± 2.018 U\L and 144.40 ± 6.50 U\L, respectively.

The correlation coefficients between age and each of serum ceruloplasmin, serum copper and hepatic copper were not significant.

Data revealed highly (P ≤ 0.01) positive correlations between age of Karadi sheep and the activity of AST (0.246) and ALT (0.267) enzymes, was found.

Data also indicate (P ≤ 0.01) negative correlation between the concentrations of ceruloplasmin in serum and the liver copper concentrations (- 0.294).

Other wise the correlations coefficient between other parameters were not significant (P < 0.05).