Study the analgesic and anti-inflammatory activity of zingiber officinale rhizome extract comparison with ibuprofen in male
Other Title(s)
دراسة الفعالية المسكنة للآلام و المضادة للالتهاب لمستخلص جذور نبات الزنجبيل : مقارنة بعقار الأبوبروفين في ذكور الفئران
Joint Authors
Ibrahim, Umar Salim
Hamid, Ahmad
Jiyad, Amir Hakim
Source
Kufa Journal for Veterinary Medical Sciences
Issue
Vol. 7, Issue 1 (30 Jun. 2016), pp.28-34, 7 p.
Publisher
University of Kufa Faculty of Veterinary Medicine
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
The aim of the present study was to explore the probable analgesic and anti-inflammatory activity of ethanolic extract of Zingiber officinale by using Hot plate test , acetic acid – induced writhing and Carrageenan induced inflammation in male mice.
Thirty Albino male mice (average weight 20g) were used and randomly divided in this study (six animals were used in each groups test for Zingiber officinale in doses of 100, 200 and 300 mg/kg B.W, Ibuprofen 20mg/kg B.W and control ( gave distilled water).The results were expressed as the Mean ±SEM and the statistical significance of differences between groups was analyzed by two Way Analysis of Variance (ANOVA) .
The extract showed a significant inhibition of writhing response and increase in hot plate reaction time and also caused significant decrease P<0.05 in paw oedema that induced by Carrageenan comparable with Ibuprofen that standard drugs used.
We can conclude from the outcome of the present work that Zingiber officinale extract exert an excellent analgesic and anti-inflammatory effect in the mice and exhibit peripheral and central analgesic effect and anti-inflammatory activity, which may be attributed to the various phytochemicals present in rhizomes of Zingiber officinale
American Psychological Association (APA)
Jiyad, Amir Hakim& Ibrahim, Umar Salim& Hamid, Ahmad. 2016. Study the analgesic and anti-inflammatory activity of zingiber officinale rhizome extract comparison with ibuprofen in male. Kufa Journal for Veterinary Medical Sciences،Vol. 7, no. 1, pp.28-34.
https://search.emarefa.net/detail/BIM-695628
Modern Language Association (MLA)
Jiyad, Amir Hakim…[et al.]. Study the analgesic and anti-inflammatory activity of zingiber officinale rhizome extract comparison with ibuprofen in male. Kufa Journal for Veterinary Medical Sciences Vol. 7, no. 1 (2016), pp.28-34.
https://search.emarefa.net/detail/BIM-695628
American Medical Association (AMA)
Jiyad, Amir Hakim& Ibrahim, Umar Salim& Hamid, Ahmad. Study the analgesic and anti-inflammatory activity of zingiber officinale rhizome extract comparison with ibuprofen in male. Kufa Journal for Veterinary Medical Sciences. 2016. Vol. 7, no. 1, pp.28-34.
https://search.emarefa.net/detail/BIM-695628
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 33-34
Record ID
BIM-695628