The effect of impaired fasting glucose on out come of patients with acute coronary syndrome

Abstract EN

Background And Objectives : diabetes mellitus is one of the major risk factor for the development of atherosclerosis that will result in multiple macro and micro vascular damage resulting in catastrophic complications, one of these major complication is the coronary heart disease in all of its spectrum that include the angina , unstable angina and non ST elevation and ST elevation MI , this spectrum of disease some time can overlap and lead to each another and call ACS (acute coronary syndrome).

The objective of this study was to estimate the major effect of acute impairment of fasting glucose on the out come and complication of ACS .

Research Design And Methods : A total of 127 patients with ACS with no previous diagnosis of diabetes were subjected to measurement of fasting blood glucose (FBG) at hospital admission in addition to HbA1c % (as it may indicate the presence of DM.

and the patient not know) ..

Based on the FBG , they were divided into those having impaired fasting glucose level( > 100mg/dl) (active group : n = 78 ) and normal glucose level(<100 mg/dl) (control group; n = 49).

Patients were followed up for mean of 10 days during the period of hospital admission.

Results: in the active group : 9 patients were died and 16 patients had heart failure, while in the control group,3 patients were died and heart failure occurred in 18 patients.

patients with FBG more than 110 mg/dl carry highest mortality .

Conclusions: Fasting blood glucose levels should be routinely assessed among patients with acute coronary syndromes , and those with impaired fasting glucose should be followed and carefully monitored for complication and those patients also should be aimed for more strong and effective therapeutic strategies like early intervention .