Blood pressure and atrial natriuretic peptide (ANP) levels in patients with autosomal dominant polycystic kidney disease
Joint Authors
al-Khafaji, Rafi Shakir
Zaydan, Haydar Kamil
al-Sadi, Ali Hammud
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 23, Issue 4 (31 Dec. 2015), pp.1451-1457, 7 p.
Publisher
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
Autosomal dominant polycystic kidney disease (ADPKD) is the most common life threatening hereditary disease of the kidney.
It is a systemic disease characterized by multiple, bilateral renal cysts that result in massive renal enlargement and progressive functional impairment.
Patients with ADPKD often develop hypertension before any abnormalities in renal function are detected clinically.
In particular, hypertension is insidious and remains a continuous problem that evolves during the course of the disease.
Atrial natriuretic peptide (ANP) possess bioactive on blood pressure.
This study dealt with two groups of patients with ADPKD; the first included the patients with renal failure while the other included the patients without renal failure, as well as healthy control group.
The results found prevalence of hypertension in patients with ADPKD, reached 75%.
Blood pressure was significant increase (P≤0.05) in ADPKD patients without renal failure than control, where reached to 137.14/85 mmHg compared with 123.93/80.71 mmHg respectively.
The ANP levels were significant increase (P≤0.05) in ADPKD patients with renal failure compared with ADPKD patients without renal failure and control groups, which reached (106.5 pg/ml), (79.2 pg/ml) and (24.4 pg/ml) respectively.
American Psychological Association (APA)
al-Khafaji, Rafi Shakir& al-Sadi, Ali Hammud& Zaydan, Haydar Kamil. 2015. Blood pressure and atrial natriuretic peptide (ANP) levels in patients with autosomal dominant polycystic kidney disease. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 23, no. 4, pp.1451-1457.
https://search.emarefa.net/detail/BIM-696726
Modern Language Association (MLA)
al-Khafaji, Rafi Shakir…[et al.]. Blood pressure and atrial natriuretic peptide (ANP) levels in patients with autosomal dominant polycystic kidney disease. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 23, no. 4 (2015), pp.1451-1457.
https://search.emarefa.net/detail/BIM-696726
American Medical Association (AMA)
al-Khafaji, Rafi Shakir& al-Sadi, Ali Hammud& Zaydan, Haydar Kamil. Blood pressure and atrial natriuretic peptide (ANP) levels in patients with autosomal dominant polycystic kidney disease. Journal of Babylon University : Journal of Applied and Pure Sciences. 2015. Vol. 23, no. 4, pp.1451-1457.
https://search.emarefa.net/detail/BIM-696726
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-696726