Estimating CD56 and perforin in rats primed by breast cancer cell line T47D
Joint Authors
al-Dulaymi, Nuaymah Hamid
al-Raji, Sad Mirza Husayn
Hasan, Ala Jawad
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 24, Issue 5 (31 Dec. 2016), pp.1214-1220, 7 p.
Publisher
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
Breast cancer is the most common disease in females and it has become a major health problem affecting women worldwide.
This study was carry out on different groups of female albino rats Rattus rattus, that primed by different forms of antigens prepared from cell line of human breast cancer T47d.
The current study has been designed to determine the immune response of rats for breast cancer cells antigens.
The immune parameters CD56 and perforin have been estimated.
Significant increase (P < 0.05) is found in the level of expression of CD56 on the surfaces of natural killer cells of rats in all treated groups, but higher level in group that injected by mixture of freezing killed antigen with adjuvant that reached to 83.164 ± 7.616 ng/ml is compared with the control groups.
The results have indicated the presence of significant increase in the level of cellular toxin perforin in all treatment groups especially the rats that immunized by freezing killed antigen with adjuvant which reached to 113.45 ± 15.925 ng/ml compared with the healthy rats.
American Psychological Association (APA)
al-Dulaymi, Nuaymah Hamid& al-Raji, Sad Mirza Husayn& Hasan, Ala Jawad. 2016. Estimating CD56 and perforin in rats primed by breast cancer cell line T47D. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 24, no. 5, pp.1214-1220.
https://search.emarefa.net/detail/BIM-697718
Modern Language Association (MLA)
al-Dulaymi, Nuaymah Hamid…[et al.]. Estimating CD56 and perforin in rats primed by breast cancer cell line T47D. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 24, no. 5 (2016), pp.1214-1220.
https://search.emarefa.net/detail/BIM-697718
American Medical Association (AMA)
al-Dulaymi, Nuaymah Hamid& al-Raji, Sad Mirza Husayn& Hasan, Ala Jawad. Estimating CD56 and perforin in rats primed by breast cancer cell line T47D. Journal of Babylon University : Journal of Applied and Pure Sciences. 2016. Vol. 24, no. 5, pp.1214-1220.
https://search.emarefa.net/detail/BIM-697718
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-697718