Study the preventive effect of aqueous extract of Gingko biloba on cerebral damage induced by ischemiareperfusion in rat
Author
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 58, Issue 2 (30 Jun. 2016), pp.183-186, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Background: cerebral damage may occur in a variety of clinical settings and this remains a significant problem.
Therefore, it seems possible that the administration aqueous extract of Gingko biloba might protect the brain against the ischemia reperfusion injury.
Objectives: The study included knowledge Phytochemical Composition and determine whether Gingko biloba in the aqueous extract prevents or decreases I/R brain damage.
Methods: Thirty rats were divided into three groups as control, I/R group and Gingko biloba treatment group.
Serum was used for the estimation of biochemical parameters: oxidative stress levels of nitric oxide (NO) and lipid peroxidation (LPO) and blood was used for the estimation of enzyme immunoassay: Interleukin-8 (IL-8), tumor necrosis factor Alpha (TNF-α), interleukin-1β (IL-1β).
Results: The results showed that the extract contain : glycosides , saponins ,tannins ,phenolic compounds , resins, flavonoids ,alkaloids and proteins.The levels of Oxidative stress in group 3 were significantly lower than those in group 2 as well as the levels of enzyme immunoassay in group 3 were significantly lower than those in group 2.
Conclusion: The present results suggest that Gingko biloba treatment protects the rat brain against ischemia-reperfusion brain damage.
American Psychological Association (APA)
Muhammad, Mustafa T.. 2016. Study the preventive effect of aqueous extract of Gingko biloba on cerebral damage induced by ischemiareperfusion in rat. Journal of the Faculty of Medicine Baghdad،Vol. 58, no. 2, pp.183-186.
https://search.emarefa.net/detail/BIM-698155
Modern Language Association (MLA)
Muhammad, Mustafa T.. Study the preventive effect of aqueous extract of Gingko biloba on cerebral damage induced by ischemiareperfusion in rat. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 2 (2016), pp.183-186.
https://search.emarefa.net/detail/BIM-698155
American Medical Association (AMA)
Muhammad, Mustafa T.. Study the preventive effect of aqueous extract of Gingko biloba on cerebral damage induced by ischemiareperfusion in rat. Journal of the Faculty of Medicine Baghdad. 2016. Vol. 58, no. 2, pp.183-186.
https://search.emarefa.net/detail/BIM-698155
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 185-186
Record ID
BIM-698155