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Spectrophotometric determination of celecoxib in pharmaeeutieal preparations
Other Title(s)
تقدير السليكوكسب طيفيا في المستحضرات الصيدلانية
Source
Journal of the College of Basic Education
Issue
Vol. 19, Issue 80 (31 Dec. 2013), pp.673-682, 10 p.
Publisher
al-Mustansiriyah University College of Basic Education
Publication Date
2013-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
Two simple and sensitive spectrophotometric methods have been developed for the estimation of Celecoxib in pure and pharinaceutical dosage forms.
Method A is based on ion association complex formation of the drug with M^h^ne Blue .
Method B is based on the charge transfer complexation reaction between Celecoxib and iodine.
The absorption spectrum of Celecoxib - m^h^ne blue and Celecoxib -iodine reaction products showed absorption peaks at 665 and 511 nm respectively.
The systems obeyed the Beer’s law in the range 0.2-1 jLig/ml for both the methods A and B.
The correlation coefficients and the limits of assays detection values were found to be 0.999, 0.37 for (method A) and 0.998, 0.426 for (method B).
, respectively, ?roposed methods were successfully applied to the qualitative determination of celecoxib in pharmaceutical dosage forms with good accuracy.
American Psychological Association (APA)
Gashim, Lamya Laftah. 2013. Spectrophotometric determination of celecoxib in pharmaeeutieal preparations. Journal of the College of Basic Education،Vol. 19, no. 80, pp.673-682.
https://search.emarefa.net/detail/BIM-705832
Modern Language Association (MLA)
Gashim, Lamya Laftah. Spectrophotometric determination of celecoxib in pharmaeeutieal preparations. Journal of the College of Basic Education Vol. 19, no. 80 (2013), pp.673-682.
https://search.emarefa.net/detail/BIM-705832
American Medical Association (AMA)
Gashim, Lamya Laftah. Spectrophotometric determination of celecoxib in pharmaeeutieal preparations. Journal of the College of Basic Education. 2013. Vol. 19, no. 80, pp.673-682.
https://search.emarefa.net/detail/BIM-705832
Data Type
Journal Articles
Language
English
Record ID
BIM-705832