Synthesis and characterization of l-alanine based poly (ester-amide)‎s

Abstract EN

Novel biomaterials L-alanine based poly(ester-amide)s (PEAs) differing in the amide/ester ratio have been directly synthesized by direct melt copolycondensation of Adipic acid, L-alanine and various aliphatic and heterocyclic diols.

PEAs were systematically characterized with intrinsic viscosity, FTIR, 1H-NMR, 13C-NMR, DSC and SEC measurements.

The resulting copolymers are amorphous and present increasing glass transition temperatures at increasing L-Alanine contents.

L-Alanine-PEAs proved to be materials having high molecular weights that could reach 41800 g/mol.