clinicopathological characteristics of primary lung cancer patients at King Hussein medical center

Abstract EN

Objective: To study the demographic and clinical features of patients diagnosed with lung cancer at our hospital and the stage of disease at presentation in various histopathology subtypes.

Methods: A retrospective descriptive study conducted in oncology clinic at King Hussein Medical City in Amman –Jordan from January 2014 till August 2015, All patients diagnosed with lung cancer in this period included in our study.

Clinical data collected from these patients include demographic data (age, sex, and smoking status), symptoms of presentation, histopathology subtype of tumor, clinical stage of disease at presentation, anatomical location, and site of metastasis at presentation.

Results: A total 112 patients included in our study; 96 male patients (85.7%) and 16 female patients (14.3%), whom age range from 22 years to 85 years with mean age of 62.2 years.

Most patients were symptomatic at presentation.

Small cell lung cancer (SCLC) was found in 23.2% (26 patients), Non- small cell lung cancer (NSCLC) in 76.8% (86 patients): (squamous cell carcinomas 59.3%, adenocarcinoma 25.2 %, Non-small cell carcinoma NOS 11.6 %, others 3.4%).88% of our patients were smokers.

Seventy percent of patients presented with metastatic disease.

Most common sites of metastasis were lung followed by liver and bone.

Conclusions: Squamous cell carcinoma was still the predominant histopathological type in our patients, which is strongly associated with smoking.

Most of our patients were symptomatic at the time of diagnosis, with significant number of those were diagnosed in metastatic stage.