Case report of a patient undergoing peritoneal dialysis with encapsulating peritoneal sclerosis superimposed with calciphylaxis

Abstract EN

Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of peritoneal dialysis (PD).

Tamoxifen has been generally well-tolerated, even without randomized controlled trials.

Case Presentation: Herein, we report a case of a patient undergoing 12 years of PD who developed EPS and calciphylaxis simultaneously.

We also provide a comprehensive discussion about the association between EPS and calciphylaxis.

Moreover, although tamoxifen is used in EPS due to its inhibition of fibroblast-transforming growth factor beta (TGF ) production, it may worsen the calciphylaxis due to a hypercoagulable state.

Conclusions: We suggest avoiding the use of tamoxifen for EPS in patients with superimposed calciphylaxis