Comparative study of lipid profile & lipid associated fucose in sera of control, minor and major thalassemic patients

Abstract EN

The aim of the present study is to evaluate the lipid profile and lipid associated fucose in sera of minor, major thalassemic and compared that with the levels of normal control.Cholesterol (Ch), Triglyceride (TG).

High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL), Very Low Density Lipoprotein (VLDL) and Lipid Associated Fucose (LAF) were determined in sera of 40 control, 40 T minor and 45 T major.

A significant elevation in cholesterol, TG, HDL and VLDL in sera of T major was found compared to the same parameters in sera of T minor and control, also a significant increase in cholesterol, TG, HDL and VLDL in sera of T major compared to T minor, also the same lipids showed a significant increase in sera of T minor compared to control.On the other hand LDL in sera of T major showed a significant reduction compared to T minor and control, also a significant decrease in LDL for T minor compared to control was found, while lipid associated fucose showed a significant increase in sera of T major over that for T minor and control, also a significant high level of LAF in sera of T minor compared to control was found.