Bacteremia due to ESKAPE pathogens : an emerging problem in cancer patients
Joint Authors
al-Mahallawi, Hadir A.
Hasan, Safa Shawqi
al-Wakil, Muhammad
Munir, Manar M.
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 28, Issue 3 (30 Sep. 2016), pp.157-162, 6 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2016-09-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and aim : In recent years, a few of the antibiotic-resistant bacteria, known as ESKAPE pathogens, have been found responsible for serious infections.
We investigated the risk factors, and impact of ESKAPE pathogens on course of blood stream infections (BSIs) in cancer patients in comparison to coagulase negative Staphylococci (CoNS).
Patients and methods : The data of patients with ESKAPE positive blood cultures at National Cancer Institute, Cairo University were analyzed.
Identification and antimicrobial susceptibility of isolates were done using Microscan Walk Away 96.
Results: In a 6 month period, ESKAPE pathogens were isolated from non-duplicate blood cultures in 81 episodes of 72 cases of pediatric cancer patients, while CoNS were isolated from 135 blood cultures of 116 patients.
The ESKAPE pathogens isolated were Enterobacter spp., methicillinresistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterococci in 12 %, 23 %, 37 %, 10 %, 9 %, and 9 % of episodes, respectively.
Health-care acquired infections constituted 75% of ESKAPE infections.
Duration of episodes and overall mortality were significantly higher in ESKAPE BSIs when compared to CoNS (14.5 ± 7.6 versus 09.9 ± 6.9), and (26 % versus 4 %); respectively, p value <0.001.
Conclusions: ESKAPE pathogens were significantly associated with higher rates of morbidity and mortality indicating the need for improving the means of prevention of these types of infections within health care premises.
Microbiology laboratories have a role in defining more dangerous infections and rapid diagnostics are required in the era of resistance
American Psychological Association (APA)
al-Mahallawi, Hadir A.& Hasan, Safa Shawqi& al-Wakil, Muhammad& Munir, Manar M.. 2016. Bacteremia due to ESKAPE pathogens : an emerging problem in cancer patients. Journal of the Egyptian National Cancer Institute،Vol. 28, no. 3, pp.157-162.
https://search.emarefa.net/detail/BIM-708840
Modern Language Association (MLA)
al-Mahallawi, Hadir A.…[et al.]. Bacteremia due to ESKAPE pathogens : an emerging problem in cancer patients. Journal of the Egyptian National Cancer Institute Vol. 28, no. 3 (Sep. 2016), pp.157-162.
https://search.emarefa.net/detail/BIM-708840
American Medical Association (AMA)
al-Mahallawi, Hadir A.& Hasan, Safa Shawqi& al-Wakil, Muhammad& Munir, Manar M.. Bacteremia due to ESKAPE pathogens : an emerging problem in cancer patients. Journal of the Egyptian National Cancer Institute. 2016. Vol. 28, no. 3, pp.157-162.
https://search.emarefa.net/detail/BIM-708840
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 162
Record ID
BIM-708840