Pathological lesions in different organs after chronic xylene and UVB exposure in mice
Other Title(s)
الإصابات المرضية في أعضاء الجسم المتعددة بعد التعرض المزمن للزايلين و الحزمة فوق البنفسجية في الفئران
Joint Authors
Hasan, Sanur Muhammad Amin
Muhammad, Iman Yasin
Mahdi, Ahmad Hamdi
Said, Azad Karim
Source
Assiut Veterinary Medical Journal
Issue
Vol. 62, Issue 150 (31 Jul. 2016), pp.10-18, 9 p.
Publisher
Assiut University Faculty of Veterinary Medicine
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Topics
Abstract EN
The present study was designed to investigate the pathological lesions in different organs induced by chronic Ultraviolet type B (UVB) and Xylene exposure in mice.
Forty mice were used in this study and divided into four groups; Group A (Control group, n=10) not exposed to UVB and Xylene, Group B (n=10) exposed to Xylene through painting the mouse’s back skin, Group C (n=10) which were exposed to UVB light only, while the remainder group (Group D, n=10) were exposed to Xylene and UVB.
The dorsal skin of mice from group B and D were painted with 1ml of Xylene whereas the animals in the group C and D exposed to UVB light for 30 minutes 4 days/week (6 weeks).
The result showed that Xylene exposure in group B produced chronic tracheitis, bronchitis with some degenerative lesions in the neurons and glial cells of the brain, no specific lesions were found in the liver, spleen and kidney.
UVB exposure in group C caused chronic tracheitis, lesions like lobar pneumonia, bronchopneumonia, and atelectasis, cellular swelling in the liver and kidney and follicular depletion in the spleen.
In group D, the lesions became more prominent when animals exposed to both Xylene and UVB.
We concluded that Xylene exposure has an adverse effect in some internal organs of mice, but not to all, when combined with UVB exposure it exaggerates its adverse effects on all of the examined organs.
American Psychological Association (APA)
Mahdi, Ahmad Hamdi& Hasan, Sanur Muhammad Amin& Said, Azad Karim& Muhammad, Iman Yasin. 2016. Pathological lesions in different organs after chronic xylene and UVB exposure in mice. Assiut Veterinary Medical Journal،Vol. 62, no. 150, pp.10-18.
https://search.emarefa.net/detail/BIM-708879
Modern Language Association (MLA)
Mahdi, Ahmad Hamdi…[et al.]. Pathological lesions in different organs after chronic xylene and UVB exposure in mice. Assiut Veterinary Medical Journal Vol. 62, no. 150 (Jul. 2016), pp.10-18.
https://search.emarefa.net/detail/BIM-708879
American Medical Association (AMA)
Mahdi, Ahmad Hamdi& Hasan, Sanur Muhammad Amin& Said, Azad Karim& Muhammad, Iman Yasin. Pathological lesions in different organs after chronic xylene and UVB exposure in mice. Assiut Veterinary Medical Journal. 2016. Vol. 62, no. 150, pp.10-18.
https://search.emarefa.net/detail/BIM-708879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 17-18
Record ID
BIM-708879