Disease-modifying drug possibly linked to placental insufficiency : severe placental complications in a pregnant woman with multiple sclerosis
Other Title(s)
الأدوية المغيرة للمرض قد تؤدي إلى قصور المشيمة : مضاعفات حادة في مشيمة امرأة حامل و مصابة بمرض التصلب المتعدد
Joint Authors
Salah al-Din, Sultan Muhammad
Begam, Muzibunnisa A.
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 16, Issue 3 (31 Aug. 2016), pp.368-370, 3 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2016-08-31
Country of Publication
Oman
No. of Pages
3
Main Subjects
Topics
- Pregnant woman
- Case studies
- Multiple sclerosis
- United Arab Emirates
- Complications(Medicine)
- Placenta
- Eclampsia
Abstract EN
Disease-modifying drugs (DMDs) such as interferon (IFN)-β and glatiramer acetate are often prescribed to slow disability progression in patients with multiple sclerosis (MS).
However, adverse pregnancy outcomes have been reported with these medications.
We report the rare occurrence of severe placental complications in a 30-yearold pregnant woman with MS who continued to take IFN-β during her first trimester.
She presented at the Tawam Hospital, Al Ain, United Arab Emirates, in 2013 with early-onset fetal growth restriction.
At 30 gestational weeks, she developed severe pre-eclampsia.
The baby was delivered via emergency Caesarean section and was discharged at the age of two months.
Continuation of IFN-β during pregnancy may have contributed to the development of placental insufficiency in this patient.
Increased education regarding the risks of DMDs for pregnant patients with MS is very important to ensure successful pregnancy outcomes
American Psychological Association (APA)
Salah al-Din, Sultan Muhammad& Begam, Muzibunnisa A.. 2016. Disease-modifying drug possibly linked to placental insufficiency : severe placental complications in a pregnant woman with multiple sclerosis. Sultan Qaboos University Medical Journal،Vol. 16, no. 3, pp.368-370.
https://search.emarefa.net/detail/BIM-709718
Modern Language Association (MLA)
Salah al-Din, Sultan Muhammad& Begam, Muzibunnisa A.. Disease-modifying drug possibly linked to placental insufficiency : severe placental complications in a pregnant woman with multiple sclerosis. Sultan Qaboos University Medical Journal Vol. 16, no. 3 (Aug. 2016), pp.368-370.
https://search.emarefa.net/detail/BIM-709718
American Medical Association (AMA)
Salah al-Din, Sultan Muhammad& Begam, Muzibunnisa A.. Disease-modifying drug possibly linked to placental insufficiency : severe placental complications in a pregnant woman with multiple sclerosis. Sultan Qaboos University Medical Journal. 2016. Vol. 16, no. 3, pp.368-370.
https://search.emarefa.net/detail/BIM-709718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 370
Record ID
BIM-709718