Systemic immunologic and inflammatory response after transperitoneal versus retroperitoneal laparoscopic donor nephrectomy : a prospective observational study
Joint Authors
Gogoi, Debojit
Bera, Malay K.
Pal, Dilip Kumar
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 5 (31 Oct. 2016), pp.985-991, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-10-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
- Kidneys
- Peritoneum
- Excision(Surgery)
- Inflammation
- Laparoscopic surgery
- Immune response
- Retroperitoneal space
Abstract EN
Laparoscopic donor nephrectomy (LDN) can be performed via either transperitoneal or retroperitoneal approach.
Very few studies have been carried out till now, comparing immunologic and inflammatory responses in donors after these two approaches.
This is a prospective observational study.
Selection of approach was decided by the operating surgeon.
All patients underwent peripheral venous blood sampling preoperatively and 24 h postoperatively for the measurement of C-reactive protein (CRP), interleukein-6 (IL-6), total leukocyte count (TLC), blood urea nitrogen (BUN), and serum creatinine (SCr).
Operative time, warm ischemia time, hospital stay, requirement of analgesia, and complications were also recorded.
From February 2013 to January 2015, we performed 54 LDNs (38 transperitoneal and 16 retroperitoneal).
There were 49 females and five males.
Mean operative time was not significantly different in these two approaches, but warm ischemia time was significantly less in the retroperitoneal laparoscopic donor nephrectomy (RLN) group.
Postoperative inflammatory markers’ (IL-6, CRP, and TLC) levels, BUN, and SCr rise in both of these approaches, but there was no significant difference observed between these two approaches.
RLN is a safe and effective approach to preserve a longer right renal vein.
It combines the benefit of both hand assistance and retroperitoneal approach.
Warm ischemic time is significantly less in RLN group.
American Psychological Association (APA)
Gogoi, Debojit& Pal, Dilip Kumar& Bera, Malay K.. 2016. Systemic immunologic and inflammatory response after transperitoneal versus retroperitoneal laparoscopic donor nephrectomy : a prospective observational study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 5, pp.985-991.
https://search.emarefa.net/detail/BIM-717124
Modern Language Association (MLA)
Gogoi, Debojit…[et al.]. Systemic immunologic and inflammatory response after transperitoneal versus retroperitoneal laparoscopic donor nephrectomy : a prospective observational study. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 5 (Sep. / Oct. 2016), pp.985-991.
https://search.emarefa.net/detail/BIM-717124
American Medical Association (AMA)
Gogoi, Debojit& Pal, Dilip Kumar& Bera, Malay K.. Systemic immunologic and inflammatory response after transperitoneal versus retroperitoneal laparoscopic donor nephrectomy : a prospective observational study. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 5, pp.985-991.
https://search.emarefa.net/detail/BIM-717124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 985-991
Record ID
BIM-717124