Association of conjunctival and corneal calcification with vascular calcification among hepatitis-C-seropositive hemodialysis patients
Joint Authors
Jabir, Mustafa
Sadiq, Ayman
Sany, Dawlah
al-Shahawi, Yasir
Abu Sayf, Khalid
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 6 (31 Dec. 2016), pp.1168-1181, 14 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-12-31
Country of Publication
Saudi Arabia
No. of Pages
14
Main Subjects
Topics
Abstract EN
Disorders associated with the hepatitis C virus (HCV) have been reported including cardiovascular, metabolic, and central nervous system diseases.
Since chronic HCV infections may be curable, their identification as causal contributors to cardiovascular risk could offer new perspectives in the prevention of cardiovascular disease.
The aim of this study is to investigate the association between HCV and aortic arch calcification (AAC) and corneal and conjunctival calcification (CCC) in maintenance hemodialysis (MHD) patients; further, we assessed the correlation of CCC with vascular calcification.
A total of 100 patients undergoing hemodialysis (HD) in our hospital were included in this study.
Patients underwent a complete ocular examination including intraocular pressure, and CCC was looked for by slit lamp and fundoscopy.
CCC was graded according to modified Porter and Crombie classification system described by Tokuyama et al.
Helical computerized tomographic chest examination was used to evaluate the grading of AAC.
Demographic, hematological, biochemical, and dialysis-related data were obtained.
There was significant difference between seropositive (n = 51) and seronegative patients (n = 49) regarding grading of AAC and CCC (P < 0.001).
In addition, CCC grading positively correlated with AAC.
Our results suggest that patients undergoing HD infected with the HCV have high degree of CCC, AAC, and mineral metabolism disorder.
The strong correlation between CCC and AAC indicates that CCC evaluation is an easy, fast, non-invasive method, and might be used as an indirect indicator to detect vascular calcification in patients undergoing MHD.
American Psychological Association (APA)
Abu Sayf, Khalid& Sany, Dawlah& al-Shahawi, Yasir& Sadiq, Ayman& al-Rahman, Khidr& Jabir, Mustafa. 2016. Association of conjunctival and corneal calcification with vascular calcification among hepatitis-C-seropositive hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 6, pp.1168-1181.
https://search.emarefa.net/detail/BIM-717262
Modern Language Association (MLA)
al-Rahman, Khidr…[et al.]. Association of conjunctival and corneal calcification with vascular calcification among hepatitis-C-seropositive hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 6 (Nov. / Dec. 2016), pp.1168-1181.
https://search.emarefa.net/detail/BIM-717262
American Medical Association (AMA)
Abu Sayf, Khalid& Sany, Dawlah& al-Shahawi, Yasir& Sadiq, Ayman& al-Rahman, Khidr& Jabir, Mustafa. Association of conjunctival and corneal calcification with vascular calcification among hepatitis-C-seropositive hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 6, pp.1168-1181.
https://search.emarefa.net/detail/BIM-717262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p.1179-1181
Record ID
BIM-717262