Facile synthesis and antimicrobial activity of a novel series of 7, 8-dihydro-2-(2 oxo-2Hchromen-3-yl)‎-5-aryl-cyclopenta [b] pyrano-pyrimidine-4, 6-5H-dione derivatives catalyzed by reusable silica-bonded N-propyl diethylenetriamine sulfamic acid

Abstract EN

An efficient method for the synthesis of a novel series of cyclopenta[b]pyrano pyrimidinone derivatives with silica-bonded N-propyl diethylenetriamine sulfamic acid (SBPDSA) as catalyst has been achieved by the condensation of 2-amino-4-phenyl-5-oxo-4,5,6,7-tetrahydrocyclopenta[b]pyran-3-carbonitrile derivatives and coumarin-3-carboxylic acid under solvent free conditions.

Antimicrobial studies showed all the target compounds processing good antibacterial and antifungal activities