Effects of Rosmarinus officinalis L. aqueous extract on acute inflammation

Joint Authors

Bu Amra, Dalila
Chekib Arslane, Baqi
Bouchebour, Abd al-Hamid
Dahamna, Saliha
Bourriche, Hamama
Samirah, Krache

Source

Sciences et Technologie : Sciences de la Nature et de la Vie

Issue

Vol. 2015, Issue 42 (31 Dec. 2015), pp.9-15, 7 p.

Publisher

University of Mentouri

Publication Date

2015-12-31

Country of Publication

Algeria

No. of Pages

7

Main Subjects

Biology
Medicine

Abstract EN

In this study, Rosmarinus officinalis L.

aqueous extract was evaluated for anti-inflammatory activity by using the model of Carrageenan-induced rat paw oedema.

Two doses of the aqueous extract (1500 mg/Kg and 3000 mg/Kg) were given orally by gavage technique, and then carrageenan was injected into the right hind paw of the rat.

The extract, which was found rich in phenolic content (196.63 ± 3.09 mg GAE/ g E) and flavonoids (2.22 ± 0.09 mg RE/ g E), has shown a good inhibitory action (44.62 % in the third hour for the higher dose.

*: p < 0.1) and close to that of aspirin that was used as a standard (31.87 % in the third hour for 200 mg/Kg aspirin.**: p < 0.05).

The same effect was observed macroscopically on the gastric ulcer for both substances.

However, the tissue alterations of the stomach were different at the histological study.

Abstract FRE

In this study, Rosmarinus officinalis L.

aqueous extract was evaluated for anti-inflammatory activity by using the model of Carrageenan-induced rat paw oedema.

Two doses of the aqueous extract (1500 mg/Kg and 3000 mg/Kg) were given orally by gavage technique, and then carrageenan was injected into the right hind paw of the rat.

The extract, which was found rich in phenolic content (196.63 ± 3.09 mg GAE/ g E) and flavonoids (2.22 ± 0.09 mg RE/ g E), has shown a good inhibitory action (44.62 % in the third hour for the higher dose.

*: p < 0.1) and close to that of aspirin that was used as a standard (31.87 % in the third hour for 200 mg/Kg aspirin.**: p < 0.05).

The same effect was observed macroscopically on the gastric ulcer for both substances.

However, the tissue alterations of the stomach were different at the histological study.

American Psychological Association (APA)

Bu Amra, Dalila& Chekib Arslane, Baqi& Bouchebour, Abd al-Hamid& Dahamna, Saliha& Bourriche, Hamama& Samirah, Krache. 2015. Effects of Rosmarinus officinalis L. aqueous extract on acute inflammation. Sciences et Technologie : Sciences de la Nature et de la Vie،Vol. 2015, no. 42, pp.9-15.
https://search.emarefa.net/detail/BIM-721641

Modern Language Association (MLA)

Bu Amra, Dalila…[et al.]. Effects of Rosmarinus officinalis L. aqueous extract on acute inflammation. Sciences et Technologie : Sciences de la Nature et de la Vie No. 42 (Dec. 2015), pp.9-15.
https://search.emarefa.net/detail/BIM-721641

American Medical Association (AMA)

Bu Amra, Dalila& Chekib Arslane, Baqi& Bouchebour, Abd al-Hamid& Dahamna, Saliha& Bourriche, Hamama& Samirah, Krache. Effects of Rosmarinus officinalis L. aqueous extract on acute inflammation. Sciences et Technologie : Sciences de la Nature et de la Vie. 2015. Vol. 2015, no. 42, pp.9-15.
https://search.emarefa.net/detail/BIM-721641

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 14-15

Record ID

BIM-721641