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Synthesis and characterization of some new pyrazoline and isoxazoline derivatives as antibacterial agents
Other Title(s)
تحضير و تشخيص بعض مشتقات البرايزولين و الأيزوكسازولين الجديدة كعوامل مضادة للبكتريا
Author
Source
Issue
Vol. 13, Issue 3 (30 Sep. 2016), pp.568-577, 10 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2016-09-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract EN
In this paper some chalcones (C1-C8) are prepared based on the reaction of one mole of substituted acetophenone with one mole of substituted benzaldehydes in the presence of (40%) sodium hydroxide as a base.
Pyrazolines (P1–P8) are prepared from the reaction of chalcones (C1-C8) with hydrazine hydrate.
Isoxazoline (I1-I8) is prepared from the reaction of chalcones (C1-C8) with hydroxyl amine hydrochloride in the presence of (10%) sodium hydroxide as a base.
These compounds are characterized by using various physical and spectral methods.
The compounds are screened for their in vitro antibacterial activity using grampositive bacteria and gram-negative bacteria.
Several derivatives of pyrazolines and isoxazolines are produced well to moderate activities against number of bacteria.
American Psychological Association (APA)
al-Nasiri, Ali Karim Ulaywi. 2016. Synthesis and characterization of some new pyrazoline and isoxazoline derivatives as antibacterial agents. Baghdad Science Journal،Vol. 13, no. 3, pp.568-577.
https://search.emarefa.net/detail/BIM-722436
Modern Language Association (MLA)
al-Nasiri, Ali Karim Ulaywi. Synthesis and characterization of some new pyrazoline and isoxazoline derivatives as antibacterial agents. Baghdad Science Journal Vol. 13, no. 3 (2016), pp.568-577.
https://search.emarefa.net/detail/BIM-722436
American Medical Association (AMA)
al-Nasiri, Ali Karim Ulaywi. Synthesis and characterization of some new pyrazoline and isoxazoline derivatives as antibacterial agents. Baghdad Science Journal. 2016. Vol. 13, no. 3, pp.568-577.
https://search.emarefa.net/detail/BIM-722436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 574-576
Record ID
BIM-722436