Role of some natural plant to enhance the immune system against exposure of ionizing radiation in experimental animals

Abstract EN

Tumor necrosis factor–alpha (TNF- α), Transforming growth factor (TGF-1β), Interleukin-5 (IL-5), liver enzymes and Malondialdehyde were determined in 50 male albino rats which are divided into 5 groups: control and 4 irradiated groups, all are exposed to the following -radiation doses: 0.5, 1, 1.5, and 2 Gy double dose for two successive weeks, once weekly.

All groups except control, 0.5 and 1 Gy groups were treated with Ambrosin extract (natural product) with 20 mg/kg body weight 8 times once weekly.

All animals were sacrificed after one week of the last dose of Ambrosin.

The results revealed that all immuno response TNF-alpha, TGF-1β and Il-5 showed a highly amelioration after treatment by Ambrosin in the groups which exposed to 1.5, and 2 Gy in comparison with the untreated groups.