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Extreme thrombocytosis presenting in anti-neutrophil cytoplasmic autoantibodies-associated crescentic glomerulonephritis with immune complex deposits : a case report
Joint Authors
Xuemei, Zhang
Yongshu, Diao
Yingying, Yang
Ping, Fu
Ling, Zhang
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 10 (31 Oct. 2016), pp.1-4, 4 p.
Publisher
Publication Date
2016-10-31
Country of Publication
United Arab Emirates
No. of Pages
4
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Introduction : We describe a female patient with extreme reactive thrombocytosis (RT) in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated crescentic glomerulonephritis (CGN) with immune complex deposits, which has never been reported before.
Case Presentation : A female adolescent with symptoms of oliguria and gross hematuresis had serious renal function impairment (crescent formation andimmunecomplex deposits in renal pathology examination with positive serum ANCA) and extreme thrombocytosis.
Wemadea diagnosis of CGNand RT.
After treatment with Prednisone, Cyclophosphamide, and plasmapheresis, the symptoms of oliguriaandgross hematuresis were relieved remarkablyandtheserumcreatinineandplatelet count declined significantly.
Conclusions : The diagnosis of thrombocytosis is not easy in all cases.
The coexistence of ANCA and the immune complex in CGN may cause a severe inflammatory state, leading to extreme RT.
The roles that the immune complex and ANCA play on the effect of the platelet count and function in CGN need further research.
American Psychological Association (APA)
Xuemei, Zhang& Yongshu, Diao& Ling, Zhang& Yingying, Yang& Ping, Fu. 2016. Extreme thrombocytosis presenting in anti-neutrophil cytoplasmic autoantibodies-associated crescentic glomerulonephritis with immune complex deposits : a case report. Iranian Red Crescent Medical Journal،Vol. 18, no. 10, pp.1-4.
https://search.emarefa.net/detail/BIM-724382
Modern Language Association (MLA)
Xuemei, Zhang…[et al.]. Extreme thrombocytosis presenting in anti-neutrophil cytoplasmic autoantibodies-associated crescentic glomerulonephritis with immune complex deposits : a case report. Iranian Red Crescent Medical Journal Vol. 18, no. 10 (Oct. 2016), pp.1-4.
https://search.emarefa.net/detail/BIM-724382
American Medical Association (AMA)
Xuemei, Zhang& Yongshu, Diao& Ling, Zhang& Yingying, Yang& Ping, Fu. Extreme thrombocytosis presenting in anti-neutrophil cytoplasmic autoantibodies-associated crescentic glomerulonephritis with immune complex deposits : a case report. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 10, pp.1-4.
https://search.emarefa.net/detail/BIM-724382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 3-4
Record ID
BIM-724382