Identification of radiation effects on carcinogenic food estimated by Ames test

Abstract EN

A major concern in studies related to carcinogenesis is the exposure to the exogenous carcinogens that may occur in food in both natural and polluted human environments.

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The purpose of the present study is to examine some of food products by Ames test to find out if food products carcinogenic then expose food to gamma radiation to find out the effect of radiation on it as a treatment.

In this study, the food samples were examined by Ames test (Salmonella typhimurium mutagenicity test) to find out that a food product could be carcinogenic or highly mutated.

Testing of chemicals for mutagenicity is based on the knowledge that a substance which is mutagenic in the bacterium is more likely than not to be a carcinogen in laboratory animals, and thus, by extension, present a risk of cancer to humans.

After that food products that showed mutagenicity exposed to gamma radiation at different doses to examine the effect of gamma radiation on food products.

This study represent γ radiation effect on carcinogenic food by using Ames test in the following steps: Detect food by Ames test using Salmonella typhimurium strains in which the colony count/plate for each food sample will show if food is slightly mutated or highly mutated or carcinogenic.

If food is highly mutated or carcinogenic with high number of colonies/plate, then the carcinogenic food or highly mutated food exposed to different doses of radiation The applied doses in this study were 0, 2.5, 5, and 10 (K Gy).

Detect the radiation effect on food samples by Ames test after irradiation.

The study shows that mutated and carcinogenic food products estimated by Ames test could be treated by irradiation.