![](/images/graphics-bg.png)
Appendicitis with positive ultrasound and its relation to total and differential leucocytic count
Joint Authors
Usayli, E. S.
Salih, G. M.
Sabik, E. A. Sh.
Ibrahim, E. M.
Source
Arab Journal of Nuclear Sciences and Applications
Issue
Vol. 49, Issue 4 (31 Oct. 2016), pp.100-113, 14 p.
Publisher
The Egyptian Society of Nuclear Science and Applications
Publication Date
2016-10-31
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Background : The most common cause of acute surgical abdomen is acute appendicitis and the most commonly done emergency surgery is appendectomy.
Although a battery of tests and different scoring methods are available for diagnosis of acute appendicitis, it is very difficult to prevent negative explorations for appendicectomy (15-30 %).
None of the tests has satisfactory Sensitivity and specificity that can be relied upon.
Objectives : The aim of the present study was to evaluate the role of total and differential leukocyte count, and ultrasonography (USG) of abdomen in diagnosing acute appendicitis and reducing the rates of negative appendicectomies and to prevent complications like perforation, peritonitis, and the longer the delay between diagnosis and surgery, the more likely is the perforation leading to peritonitis.
In addition, emphasis was given to whether combining the investigations for the same patient would improve the diagnostic accuracy.
Materials and Methods: A total of 76 clinically diagnosed patients of acute appendicitis, posted for emergency appendicectomy were included in the study in General Surgery Department of EL-Salam Hospital.
This study was conducted in the period October 2012 to September 2013.
Preoperatively blood tests for, total leukocyte count, differential leukocyte count (DLC) and USG abdomen were done.
All patients were subjected to histological examination postoperatively, which was taken as the gold standard.
The three investigations results were correlated with histo-pathological examination reports to evaluate their role in diagnosis of acute appendicitis.
Results : In the present study, the US has the highest sensitivity and specificity (90%, 80%) followed by Total leucocytic count (87.5%, 90%), white Neutrophil count (78.75%, 80%).
Combining US and WBC count increases the sensitivity and specificity of the tests (96.25%, 80%).
Conclusion : US contains important diagnostic information and hence should always be included in the diagnostic workup of acute appendicitis.
The sensitivity of WBC count and DLC are low individually, but when combined with US the sensitivity and specificity increases.
When all three tests are negative acute appendicitis is very unlikely and surgery can be safely deferred in these patients thereby reducing the negative appendicectomy rates.
American Psychological Association (APA)
Salih, G. M.& Sabik, E. A. Sh.& Usayli, E. S.& Ibrahim, E. M.. 2016. Appendicitis with positive ultrasound and its relation to total and differential leucocytic count. Arab Journal of Nuclear Sciences and Applications،Vol. 49, no. 4, pp.100-113.
https://search.emarefa.net/detail/BIM-724598
Modern Language Association (MLA)
Salih, G. M.…[et al.]. Appendicitis with positive ultrasound and its relation to total and differential leucocytic count. Arab Journal of Nuclear Sciences and Applications Vol. 49, no. 4 (Oct. 2016), pp.100-113.
https://search.emarefa.net/detail/BIM-724598
American Medical Association (AMA)
Salih, G. M.& Sabik, E. A. Sh.& Usayli, E. S.& Ibrahim, E. M.. Appendicitis with positive ultrasound and its relation to total and differential leucocytic count. Arab Journal of Nuclear Sciences and Applications. 2016. Vol. 49, no. 4, pp.100-113.
https://search.emarefa.net/detail/BIM-724598
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 112-113
Record ID
BIM-724598