Health-related quality of life in children with chronic hepatitis C
Author
Source
Egyptian Pediatric Association Gazette
Issue
Vol. 64, Issue 3 (30 Sep. 2016), pp.120-125, 6 p.
Publisher
Egyptian Pediatric Association
Publication Date
2016-09-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background : Mood disturbances, including depression, are relatively common in the hepatitis C virus-infected population and may worsen during hepatitis C treatment, also hepatitis C virus infection is associated with decreased quality of life (QOL) and neurocognitive dysfunction in adults, but little is known about its impact on children.
Aim of the study: To assess the health-related quality of life (HRQOL), behavioral/emotional functioning, and cognitive status of children with hepatitis C infection with and without treatment.
Methods : A total of 120 children who were divided into three groups: group 1: 30 chronic hepatitis C infected children without treatment, group II: 30 chronic hepatitis C infected children under treatment with peg-interferon and ribavirin, group III: Includes 60 normal children matched for age and sex as a control group were enrolled in this case–control study.
We used the Peds QLTM 4.0 generic score scale to assess the HRQOL based on a child’s self- and parent proxy reports.
Also assessment of childhood depression using ACDS Inventory, Arabic form based on Kovacs Children’s Depression Inventory was done.
Results : There was a statistical significant difference between studied groups regarding physical, emotional, social and school functioning parameter of parents’ reports and child opinion of PEDSQL score, also there was a statistical significant difference between studied groups regarding depression score as it was significantly higher in group II (hepatitis C infected children under treatment with peg-interferon and ribavirin).
Conclusion : HRQOL and depression scores were significantly increased in children with chronic hepatitis C however both were higher in children receiving treatment.
American Psychological Association (APA)
Buhayri, Ula Jalal Ali. 2016. Health-related quality of life in children with chronic hepatitis C. Egyptian Pediatric Association Gazette،Vol. 64, no. 3, pp.120-125.
https://search.emarefa.net/detail/BIM-726149
Modern Language Association (MLA)
Buhayri, Ula Jalal Ali. Health-related quality of life in children with chronic hepatitis C. Egyptian Pediatric Association Gazette Vol. 64, no. 3 (Sep. 2016), pp.120-125.
https://search.emarefa.net/detail/BIM-726149
American Medical Association (AMA)
Buhayri, Ula Jalal Ali. Health-related quality of life in children with chronic hepatitis C. Egyptian Pediatric Association Gazette. 2016. Vol. 64, no. 3, pp.120-125.
https://search.emarefa.net/detail/BIM-726149
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 124-125
Record ID
BIM-726149