Combination of Nigella sativa and honey in eradication of gastric helicobacter pylori infection
Joint Authors
Shirazi, Maryam Taghavi
Ghobadi, Ali
Dabaghian, Fataneh Hashim
Agah, Shahram
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 11 (30 Nov. 2016), pp.1-6, 6 p.
Publisher
Publication Date
2016-11-30
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Background : Gastric Helicobacter pylori is extremely common worldwide.
Objectives : The aim of this study was to assess the effectiveness of combination of Nigella sativa and honey (Dosin) in eradication of gastric H.
pylori infection.
Patients and Methods : Nineteen patients who had positive result for H.
pylori infection by urea breath test (UBT) without a past history of peptic ulcer, gastric cancer or gastrointestinal bleeding, were suggested to receive one teaspoon of the mixture of Dosin (6 g / day of N.
sativa as ground seeds and 12 g / day of honey) three times a day after meals for two weeks.
The second UBT was used to detect the presence of H.
pylori four weeks after completion of the test.
In addition, symptoms of dyspepsia were scored before and after the study and analyzed with Wilcoxon signed-rank test Results : Fourteen patients completed the study.
Negative UBT was observed in 57.1% (8 / 14) of participants after intervention.
The median and interquartile range (IQR) of total dyspepsia symptoms was significantly reduced from 5.5 (5 -12) to 1 (0 - 4) (P = 0.005).
All the patients tolerated Dosin except for one who was excluded due to mild diarrhea.
No serious adverse events were reported.
Conclusions : Dosin was concluded to be an anti H.
pylori and an anti-dyspeptic agent.
Further studies are recommended to investigate the effect of Dosin plus antibiotics (concurrently or following another) on gastric H.
pylori infection.
American Psychological Association (APA)
Dabaghian, Fataneh Hashim& Agah, Shahram& Shirazi, Maryam Taghavi& Ghobadi, Ali. 2016. Combination of Nigella sativa and honey in eradication of gastric helicobacter pylori infection. Iranian Red Crescent Medical Journal،Vol. 18, no. 11, pp.1-6.
https://search.emarefa.net/detail/BIM-728721
Modern Language Association (MLA)
Dabaghian, Fataneh Hashim…[et al.]. Combination of Nigella sativa and honey in eradication of gastric helicobacter pylori infection. Iranian Red Crescent Medical Journal Vol. 18, no. 11 (Nov. 2016), pp.1-6.
https://search.emarefa.net/detail/BIM-728721
American Medical Association (AMA)
Dabaghian, Fataneh Hashim& Agah, Shahram& Shirazi, Maryam Taghavi& Ghobadi, Ali. Combination of Nigella sativa and honey in eradication of gastric helicobacter pylori infection. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 11, pp.1-6.
https://search.emarefa.net/detail/BIM-728721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 5-6
Record ID
BIM-728721