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Effects of fish oil supplementation on Gestational Diabetes Mellitus (GDM) : a systematic review
Joint Authors
Ostadrahimi, Alireza
Alizadeh, Muhammad Sakineh
Mirgafourvand, Mozhgan
Yaqubi, Sina
Shahrisa, Ilham
Khalili, Azizah Farshbaf
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 11 (30 Nov. 2016), pp.1-10, 10 p.
Publisher
Publication Date
2016-11-30
Country of Publication
United Arab Emirates
No. of Pages
10
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Context : One of the most common complications of pregnancy is gestational diabetes mellitus (GDM), which is increasing worldwide.
Experimental and epidemiological studies have shown that higher intake of n-3 long-chain polyunsaturated fatty acids may decrease the risk of various diseases such as diabetes.
The objective of this study was to assess the effect of fish oil supplementation on the prevention and treatment of GDM.
Evidence Acquisition: This systematic review was performed by searching several databases, including PubMed, Scopus, Google Scholar, the Cochrane Library, ProQuest, Science Direct SID, Magiran and IranMedex since 1983.
The researchers also searched for references in reviewed clinical trial articles in which fish oil supplementation was compared with placebo or no supplementation.
Results : Only two published and in-press articles are included in this review.
Based on these studies, docosahexaenoic acid (DHA)- enriched fish oil (800 mg/d) had no effect on prevention of GDM [0.97 (95% CI: 0.74, 1.27)].
Furthermore, omega-3 fatty acid supplementation containing 180mgof eicosapentaenoic acid (EPA) and 120mgDHA had beneficial effects on insulin resistance in women with GDM (change from baseline: 1.5_7.5 vs 3.5_8.5 mIU/mL, P = 0.02) but did not influence fasting plasma glucose, homeostatic model assessment-Beta cell function (HOMA-B), the quantitative insulin sensitivity check index (QUICKI), or lipid profiles (P > 0.05).
Conclusions : There is not enough evidence to support or refute the routine use of fish oil supplements during pregnancy for the prevention or treatment of diabetes.
It is suggested that further randomized controlled trials be conducted to evaluate the role of fish oil supplementation in pregnancy.
American Psychological Association (APA)
Ostadrahimi, Alireza& Alizadeh, Muhammad Sakineh& Mirgafourvand, Mozhgan& Yaqubi, Sina& Shahrisa, Ilham& Khalili, Azizah Farshbaf. 2016. Effects of fish oil supplementation on Gestational Diabetes Mellitus (GDM) : a systematic review. Iranian Red Crescent Medical Journal،Vol. 18, no. 11, pp.1-10.
https://search.emarefa.net/detail/BIM-728729
Modern Language Association (MLA)
Ostadrahimi, Alireza…[et al.]. Effects of fish oil supplementation on Gestational Diabetes Mellitus (GDM) : a systematic review. Iranian Red Crescent Medical Journal Vol. 18, no. 11 (Nov. 2016), pp.1-10.
https://search.emarefa.net/detail/BIM-728729
American Medical Association (AMA)
Ostadrahimi, Alireza& Alizadeh, Muhammad Sakineh& Mirgafourvand, Mozhgan& Yaqubi, Sina& Shahrisa, Ilham& Khalili, Azizah Farshbaf. Effects of fish oil supplementation on Gestational Diabetes Mellitus (GDM) : a systematic review. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 11, pp.1-10.
https://search.emarefa.net/detail/BIM-728729
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 9-10
Record ID
BIM-728729