Maternal inactive hepatitis B status and birth-outcomes : a systematic review and meta-analysis
Joint Authors
Montazeri, Ali
Ibrahimi, Ilham
Abedini, Mehrandokht
Yunesian, Masud
Khosravi, Ahmad
Keramat, Afsaneh
Alavian, Sayyid Muayyad
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 11 (30 Nov. 2016), pp.1-13, 13 p.
Publisher
Publication Date
2016-11-30
Country of Publication
United Arab Emirates
No. of Pages
13
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Context : Hepatitis is a term used to describe any type of hepatitis inflammation.
Screening for the virus antigen during pregnancy is mandatory in some parts of the world and is recommended in others.
so that, most women are aware of and understand the disease if they have it when they are pregnant.
Thus, the major concerns of these women are both the virus transmission to the fetus and the effects of hepatitis B on pregnancy outcome.
Evidence Acquisition: According to a specific protocol, we searched in the Pub med, Scopus, ISI web of science from 1990 to February 2015 to find the original articles, which investigated the hepatitis B effects in pregnantwomenwith normal singleton pregnancy who were previously diagnosed with inactive CHB or were incidentally found to be HBsAg positive in routine antenatal blood test.
We included any cohort, case control and cross sectional studies if they had a healthy control group and reported one or more considered maternal or prinatal outcomes in pregnant women.
Meta-analysis was performed with Review manager 5.4 and Stata 11 software.
We assessed the effect size that was pooled odds ratio (OR) and 95 % confidence intervals (CIs) using the random effects model.
We explored statistical heterogeneity using the chi-squared (Chi2), I2 and tau-squared (Tau2) statistical tests.
Results : From a total of 156 identified studies, 56 studies were chosen for a detailed review, and 18 studies whichmet the inclusion and exclusion criteria were included in the meta analysis.
Among the included studies, the outcomes were small for gestational age (SGA) large for gestational age (LGA), intra uterine growth restriction (IUGR), fetal distress, fifth minutes apgar score, first minute Apgar score, low birth weight (LBW) and Fetal Macrosomia.
Conclusions : In this study, hepatitis B had a cause effect on LGA and fetal Macrosomia.
Among the other considered adverse pregnancy outcomes; it didn’t have any significant effect.
American Psychological Association (APA)
Ibrahimi, Ilham& Keramat, Afsaneh& Yunesian, Masud& Alavian, Sayyid Muayyad& Khosravi, Ahmad& Montazeri, Ali…[et al.]. 2016. Maternal inactive hepatitis B status and birth-outcomes : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal،Vol. 18, no. 11, pp.1-13.
https://search.emarefa.net/detail/BIM-728750
Modern Language Association (MLA)
Ibrahimi, Ilham…[et al.]. Maternal inactive hepatitis B status and birth-outcomes : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal Vol. 18, no. 11 (Nov. 2016), pp.1-13.
https://search.emarefa.net/detail/BIM-728750
American Medical Association (AMA)
Ibrahimi, Ilham& Keramat, Afsaneh& Yunesian, Masud& Alavian, Sayyid Muayyad& Khosravi, Ahmad& Montazeri, Ali…[et al.]. Maternal inactive hepatitis B status and birth-outcomes : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 11, pp.1-13.
https://search.emarefa.net/detail/BIM-728750
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 10-13
Record ID
BIM-728750