Re-irradiation for head and neck squamous cell carcinoma
Joint Authors
Rath, Goura Kishor
Benson, Rony
Mallick, Supriya
Venkatesulu, Bhanu Prasad
Giridhar, Prashanth
Rida, Muhammad Wasim
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 29, Issue 1 (31 Mar. 2017), pp.1-9, 9 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2017-03-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Introduction: Local recurrences after curative treatment have a potential for cure with salvage surgery or with re-irradiation.
Methods: We reviewed the PubMed for articles published in English with key words squamous cell carcinoma, recurrent, re-irradiation, prognostic factors to find relevant articles describing prognostic factors, re-irradiation, and outcome for recurrent head and neck squamous cell carcinoma.
Results: Various factors including age, performance status, time for recurrence, previous radiation dose volume and site of recurrence, previous use of chemotherapy are all prognostic factors in recurrent head and neck squamous cell carcinoma.
Surgery is feasible in very select subgroup of patients and must be done when feasible.
Re-irradiation with the aid of modern sophisticated technology is safe and confers durable and clinically meaningful survival benefit.
Re-irradiation in head and neck recurrent squamous cell carcinoma may provide an expected median survival of 10– 12 months.
Chemotherapy may be added along with radiation in the recurrent setting.
Conclusion: Treatment approaches may have to be personalized.
Re surgery must be done in all patients in whom it is feasible.
In patients in whom surgery is not feasible, re-irradiation must be evaluated as a therapeutic option especially in patients with limited volume recurrence.
American Psychological Association (APA)
Benson, Rony& Giridhar, Prashanth& Venkatesulu, Bhanu Prasad& Mallick, Supriya& Rida, Muhammad Wasim& Rath, Goura Kishor. 2017. Re-irradiation for head and neck squamous cell carcinoma. Journal of the Egyptian National Cancer Institute،Vol. 29, no. 1, pp.1-9.
https://search.emarefa.net/detail/BIM-733769
Modern Language Association (MLA)
Benson, Rony…[et al.]. Re-irradiation for head and neck squamous cell carcinoma. Journal of the Egyptian National Cancer Institute Vol. 29, no. 1 (Mar. 2017), pp.1-9.
https://search.emarefa.net/detail/BIM-733769
American Medical Association (AMA)
Benson, Rony& Giridhar, Prashanth& Venkatesulu, Bhanu Prasad& Mallick, Supriya& Rida, Muhammad Wasim& Rath, Goura Kishor. Re-irradiation for head and neck squamous cell carcinoma. Journal of the Egyptian National Cancer Institute. 2017. Vol. 29, no. 1, pp.1-9.
https://search.emarefa.net/detail/BIM-733769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 7-9
Record ID
BIM-733769