Association between Hla and Guillain Barre' syndrome
Author
Source
al-Kindy College Medical Journal
Issue
Vol. 12, Issue 1 (30 Jun. 2016), pp.109-111, 3 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Abstract EN
Background : Genetic factors play an important role in susceptibility to Guillain Barre' syndrome.
Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.
Aim of the study: to assess the relationship between HLA-A alleles with Guillain Barre' syndrome (GBS) compared with a healthy control group using PCR-SSOP method.
Type of the study: Cross-sectional study.
Patients and methods:Patient's group consisted of 30 Iraqi Arab Muslims patients with Guillain Barre' syndrome that consulted the Neurological department in Neurosciences Hospital between January-2013 to January- 2014 were genotyped for HLA-A alleles.
A control group consisted of 30 healthy volunteers among the staff of AL-Kindi College of Medicine that did not have any neurological disorders.
Results : Present study found a decreased frequency of HLA-A:0101 allele (p=0.001) in GBS patients compared to healthy controls.
Conclusions: current results suggest that GBS is negatively associated with HLA-A:0101 allele.
American Psychological Association (APA)
Rauf, Hiyam. 2016. Association between Hla and Guillain Barre' syndrome. al-Kindy College Medical Journal،Vol. 12, no. 1, pp.109-111.
https://search.emarefa.net/detail/BIM-739743
Modern Language Association (MLA)
Rauf, Hiyam. Association between Hla and Guillain Barre' syndrome. al-Kindy College Medical Journal Vol. 12, no. 1 (2016), pp.109-111.
https://search.emarefa.net/detail/BIM-739743
American Medical Association (AMA)
Rauf, Hiyam. Association between Hla and Guillain Barre' syndrome. al-Kindy College Medical Journal. 2016. Vol. 12, no. 1, pp.109-111.
https://search.emarefa.net/detail/BIM-739743
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 111
Record ID
BIM-739743