متلازمة الاستجابة الالتهابية الجهازية كمشعر إنذاري في تشمع الكبد
Other Title(s)
Systemic inflammatory response syndrome as a prognostic index in cirrhosis
Joint Authors
Source
Issue
Vol. 30, Issue 1 (30 Jun. 2014), pp.63-72, 10 p.
Publisher
Publication Date
2014-06-30
Country of Publication
Syria
No. of Pages
10
Main Subjects
Abstract EN
Background& Objective: There is Some evidence to suggest that the systemic inflammatory response syndrome (SIRS) contributes to the poor outcome of cirrhotic patients.
We studied 95 cirrhotic patients admitted to Almouassat and Al-assad University Hospitals assessing prevalence of SIRS and its relationship with short term outcome.
Materials & Methods: Presence of SIRS was assessed on admission and during hospital stay.
First end point was death and development of portal hypertension-related complications within their in-hospital stay.
Second end point was death within 90 days from admittion, only 60 patients were followed to the second end point.
Results: About one-half the patients met SIRS criteria.
SIRS was correlated with complications in general (p = 0.003), high serum bilirubin levels (p = 0.008), high international normalized ratio (p = 0.004), low serum albumin (p=0.004), and high model of endstage liver disease (MELD) score (p = 0.0003), During a follow-up of 7 ± 2 days, 8 patients died (8.4%), 11 developed portal hypertension-related bleeding (11.6%), 26 hepatic encephalopathy (27.4%), and 9 hepatorenal syndrome type-1 (9.5%).
SIRS was correlated both to death (p = 0.03) and to portal hypertensionrelated complications (p = 0.003).
From the patients who were followed to 90 days after admittion; SIRS was significantly correlated to death (p = 0.0005).
Conclusions: SIRS frequently occurs in patients with advanced cirrhosis and is associated with a poor outcome.
American Psychological Association (APA)
حفار، سمير والمصري، بشار. 2014. متلازمة الاستجابة الالتهابية الجهازية كمشعر إنذاري في تشمع الكبد. مجلة جامعة دمشق للعلوم الطبية،مج. 30، ع. 1، ص ص. 63-72.
https://search.emarefa.net/detail/BIM-743328
Modern Language Association (MLA)
حفار، سمير والمصري، بشار. متلازمة الاستجابة الالتهابية الجهازية كمشعر إنذاري في تشمع الكبد. مجلة جامعة دمشق للعلوم الطبية مج. 30، ع. 1 (2014)، ص ص. 63-72.
https://search.emarefa.net/detail/BIM-743328
American Medical Association (AMA)
حفار، سمير والمصري، بشار. متلازمة الاستجابة الالتهابية الجهازية كمشعر إنذاري في تشمع الكبد. مجلة جامعة دمشق للعلوم الطبية. 2014. مج. 30، ع. 1، ص ص. 63-72.
https://search.emarefa.net/detail/BIM-743328
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 71-72
Record ID
BIM-743328