The antimicrobial and wound healing effect of Aloe Vera in induced diabetic rats
Other Title(s)
الفعالية المضادة للميكروبات و المحفزة على التئام الجروح لنبات الصبار Aloe Vera في الجرذان المستحثة الإصابة بداء السكري
Author
Jawad, Rafat Abd al-Hasan Muhammad
Source
al-Qadisiyah Journal of Veterinary Medicine Sciences
Issue
Vol. 13, Issue 1 (30 Jun. 2014), pp.7-14, 8 p.
Publisher
al-Qadisiyah University College of Veterinary Medicine
Publication Date
2014-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
The study was conducted on sixteen streptozotocin induced diabetic rats to investigate whether the topical application of Aloe Vera gel and alcoholic Aloe Vera leaf extract could improve the wound healing in diabetic rats.
The rats were weight, matched, and placed in to four groups 4 rats of each group.
Full thickness circular skin wound (2cm in diameter) was experimentally created dorsal to the neck area of each rat.
Animals in group (1) left without dressing as a control group.
Animals in group (2 and 3) were treated topically with Aloe Vera gel (100%) and alcoholic Aloe Vera leaf extracts (100%) respectively, while the animals of group (4) were treated with povidone iodine (4%).
Treated groups were dresses twice daily for 14 successive days.
The treated wound in groups 2, and 3 were significantly healed faster in comparison to the wound of control group.
The effect produced by the Aloe Vera with reference to the wound contraction, wound closure, decreased in surfaces area of wound, and tissue regeneration at the wound site.
Histologically wounds treated with Aloe Vera show increase in macrophages, fibroblast migration, collagen regeneration and epithelialization compared with the control group.
The wet, dry granulation tissue weight, and hydroxyproline content increased significantly when compared to control.
Aloe Vera was seen exhibited antimicrobial activity against some pathogenic microorganism.
In conclusion Aloe Vera have strong wound healing property and effective as topical preparation and formulated as fairly economical therapeutic agent for wound management.
American Psychological Association (APA)
Jawad, Rafat Abd al-Hasan Muhammad. 2014. The antimicrobial and wound healing effect of Aloe Vera in induced diabetic rats. al-Qadisiyah Journal of Veterinary Medicine Sciences،Vol. 13, no. 1, pp.7-14.
https://search.emarefa.net/detail/BIM-743467
Modern Language Association (MLA)
Jawad, Rafat Abd al-Hasan Muhammad. The antimicrobial and wound healing effect of Aloe Vera in induced diabetic rats. al-Qadisiyah Journal of Veterinary Medicine Sciences Vol. 13, no. 1 (2014), pp.7-14.
https://search.emarefa.net/detail/BIM-743467
American Medical Association (AMA)
Jawad, Rafat Abd al-Hasan Muhammad. The antimicrobial and wound healing effect of Aloe Vera in induced diabetic rats. al-Qadisiyah Journal of Veterinary Medicine Sciences. 2014. Vol. 13, no. 1, pp.7-14.
https://search.emarefa.net/detail/BIM-743467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 13-14
Record ID
BIM-743467