دراسة جرثومية عشوائية ثنائية التعمية للأزيترومايسين الجهازي كمعالجة داعمة للتقليح و تسوية الجذور لالتهاب الأنسجة حول السنية الاجتياحي
Other Title(s)
Microbiological study of azithromycine administration as adjunctive therapy of aggressive periodontitis. randomized, double-blind controlled clinical trail
Author
Source
Issue
Vol. 29, Issue 1 (30 Jun. 2013), pp.469-481, 13 p.
Publisher
Publication Date
2013-06-30
Country of Publication
Syria
No. of Pages
13
Main Subjects
Abstract EN
Background & Objective: This study is carried out by using PCR technique to assess the efficacy of systemic azithromycin as a supplement to scaling and root planning (SRP) in the treatment of aggressive periodontitis (AgP) in three months follow up on the periodontal pathogens compared with a control group.
Materials&Methods: 26 patients, 14–28 years old (mean 21y) were examined with aggressive periodontitis in the Department of Periodontology in Damascus university, the study was double-blind.
All subjects received scaling and root planning in one session, and randomized into 2 groups, the test group(13 patients) was treated with supplementary azithromycin 500 mg tablets once daily for 3 days, the control(13 patients) group was administered placebo tablets (Al Fares company-Syria).
And subgingival plaque was collected from the deepest 5 pockets using paper strips (N=260) before treatment and 3 months postoperatively.
The plaque samples were used to assess presence of 11 periodontal bacteria using the micro-IDent®plus Test (Hain Lifescience, Nehren, Germany).
Mann-Whitney and Wilcoxon were used to compare group means.
Results: The periodontal pathogens in the test group before treatment was between (12.5 ,17.08), and in the placebo group was (14.5 ,9.92), and had a significant decrease after 3 months (p<0.05) in the number of sites with detectable Aa, Pg, Tf, Fn, Td, and Cr.
An increase in detectable bacteria was for all bacteria and significantly in (P=0.04) Pm, (P=0.02) En in the control group.
Conclusion: The use of azithromycin as a supplement to scaling and root planning in treatment of aggressive periodontitis significantly reduces the number of sites with detectable periodontal pathogens
American Psychological Association (APA)
حورية، رشا. 2013. دراسة جرثومية عشوائية ثنائية التعمية للأزيترومايسين الجهازي كمعالجة داعمة للتقليح و تسوية الجذور لالتهاب الأنسجة حول السنية الاجتياحي. مجلة جامعة دمشق للعلوم الطبية،مج. 29، ع. 1، ص ص. 469-481.
https://search.emarefa.net/detail/BIM-745081
Modern Language Association (MLA)
حورية، رشا. دراسة جرثومية عشوائية ثنائية التعمية للأزيترومايسين الجهازي كمعالجة داعمة للتقليح و تسوية الجذور لالتهاب الأنسجة حول السنية الاجتياحي. مجلة جامعة دمشق للعلوم الطبية مج. 29، ع. 1 (2013)، ص ص. 469-481.
https://search.emarefa.net/detail/BIM-745081
American Medical Association (AMA)
حورية، رشا. دراسة جرثومية عشوائية ثنائية التعمية للأزيترومايسين الجهازي كمعالجة داعمة للتقليح و تسوية الجذور لالتهاب الأنسجة حول السنية الاجتياحي. مجلة جامعة دمشق للعلوم الطبية. 2013. مج. 29، ع. 1، ص ص. 469-481.
https://search.emarefa.net/detail/BIM-745081
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 480-481
Record ID
BIM-745081