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The relation between endometrial thickness and serum estradiol (E2), progesterone levels in different protocols of controlled ovarian stimulation and its impact on intracytoplasmic sperm injection (ICSI) outcome
Other Title(s)
العلاقة بين مستوى هرمون الاستراديول و مستوى هرمون البروجسنيرون بالدم و سمك البطانة الرحمية أثناء استخدام البروتوكولات المختلفة لتنشيط التبويض و علاقة ذلك البروتوكولات المختلفة لتنشيط التبويض و علاقة ذلك بناتج عملية الحقن المجهري
Joint Authors
Mansur, Siraj al-Din
Abd al-Al, Hani Majid
Hasan, Nabil Abd al-Maqsud
Faraj, Abd al-Munim Muhammad
Shaban, Muhammad Rida
Hasan, Farid Ibrahim
Source
Reproductive Health and Population Sciences Journal
Issue
Vol. 2015, Issue 40 (31 Jan. 2015), pp.241-263, 23 p.
Publisher
Al-Azhar University International Islamic Center for Population Studies and Research
Publication Date
2015-01-31
Country of Publication
Egypt
No. of Pages
23
Main Subjects
Abstract EN
Background : Many stimulation cycles in assisted reproduction are associated with failed pregnancy despite the transfer of apparently healthy and morphologically normal embryos.
This suggests abnormal endometrial thickness in response to alteration in serum estradiol (E2) and progesterone (P) levels.
Aim: To determine the impact of serum eostrogen (E2) and progesterone levels on ICSI outcome, and to investigate the relationship between endometrial thickness measurement and its impact on ICSI outcome.
Study Design: This study was carried out on 100 infertile women who were assigned for ovarian stimulation using the different protocols applied in the Assisted Reproduction Unit in Al-Azhar University (International Islamic centre for population studies and research).All patients included in the study were subjected to:Basal serum FSH, LH & PRL were done on day 3of cycle.
Serum estradiol (E2) measurement was done basal, at day of HCG administration and at day of embryo transfer (ET).Serum progesterone measurement was done at day of embryo transfer (ET).Endometrial thickness was measured during folliculometry starting from day 7 of cycle especially at the day of HCG administration.
Results: Statistical analysis of the results show that an increase of endometrial thickness at HCG day and progesterone at ET would increase the probability of positive pregnancy by about 40% and 20% respectively.
The difference between endometrial thickness at folliculometry and at HCG day (Δ endometrial thickness) was also found to be positively and significantly associated with positive pregnancy.
Increasing the difference would increase the probability of positive pregnancy by 30% (OR= 1.30; 95% CI= 1.05 – 1.58).
Conclusion: Endometrial thickness is effective parameter for detection of ICSI outcome.Enodometrial thickness (at day of HCG) more than 9mm and less than 15mm can be used as indicator of good pregnancy outcome.
American Psychological Association (APA)
Mansur, Siraj al-Din& Abd al-Al, Hani Majid& Hasan, Nabil Abd al-Maqsud& Faraj, Abd al-Munim Muhammad& Hasan, Farid Ibrahim& Shaban, Muhammad Rida. 2015. The relation between endometrial thickness and serum estradiol (E2), progesterone levels in different protocols of controlled ovarian stimulation and its impact on intracytoplasmic sperm injection (ICSI) outcome. Reproductive Health and Population Sciences Journal،Vol. 2015, no. 40, pp.241-263.
https://search.emarefa.net/detail/BIM-746027
Modern Language Association (MLA)
Mansur, Siraj al-Din…[et al.]. The relation between endometrial thickness and serum estradiol (E2), progesterone levels in different protocols of controlled ovarian stimulation and its impact on intracytoplasmic sperm injection (ICSI) outcome. Reproductive Health and Population Sciences Journal No. 40 (Jan. 2015), pp.241-263.
https://search.emarefa.net/detail/BIM-746027
American Medical Association (AMA)
Mansur, Siraj al-Din& Abd al-Al, Hani Majid& Hasan, Nabil Abd al-Maqsud& Faraj, Abd al-Munim Muhammad& Hasan, Farid Ibrahim& Shaban, Muhammad Rida. The relation between endometrial thickness and serum estradiol (E2), progesterone levels in different protocols of controlled ovarian stimulation and its impact on intracytoplasmic sperm injection (ICSI) outcome. Reproductive Health and Population Sciences Journal. 2015. Vol. 2015, no. 40, pp.241-263.
https://search.emarefa.net/detail/BIM-746027
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 259-260
Record ID
BIM-746027