دراسة العلاقة بين مستويات العقد اللمفية و خصائص السرطان شائك الخلايا في الشفة السفلية

Abstract EN

Background & Objective: Cancer of the lip is relatively common malignancy of the head and neck region.

Squamous cell carcinoma most frequently occurs in the lower lip (LLSCC) or Lower Lip Squamous Cell Carcinoma.

This study aimed to evaluate the correlation between the involved lymph nodes level and the tumor appearance, greatest dimension (T) and its degree of differentiation.

Materials & Methods: The sample consisted of 25 patients (21 M, 4 F) who suffered from lower lip squamous cell carcinoma between 2009 and 2011 in Al Moasat hospital.

All patients underwent planned surgical resection of the malignant lesion of the lower lip.

Patients were classified according to TNM then the involved lymph nodes level and the differentiation degree were determined for every patient.

All of the patient age, the involved lymph nodes level, the tumor appearance, the greatest dimension, and the differentiation were recorded.

statistical study: CHI- square test was done to determine the correlation between the involved lymph nodes level and the tumor appearance, its greatest dimension, and its degree of differentiation at confidence level 95% (P<0.05).

Results: The patients were divided according to T as the following ( 24% T1, 56%T2, 12% T3, 8%T4) whereas they were divided according to G ( 16%G1, 64% G2, 16%G3, 4%G4).

Metastases to level Ia was found in 16% of patients and 8% to the level I (a+b) and only 4% to the level II , in contrast 72% of patients were without lymphatic involvement.

This study showed a correlation between the involved lymphatic level on one side and the tumor appearance, its greatest dimension , and its grade on the other side.

There was no statistical relation between the age and the tumor diameter or its grade.

Conclusion: The possibility of Locoregional lymphatic metastases occurrence increases when the tumor diameter becomes longer or when the tumor differentiation becomes poorer whatever is the patient’s age.