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Evaluation of T-helper 22 and T-helper 17 in patients with breast cancer
Joint Authors
al-Khafaf, Dina M. R.
al-Umari, Raghdah S. M.
al-Khuzai, Ziyad Mutib Fajh
Source
al-Kufa University Journal for Biology
Issue
Vol. 8, Issue 3 (31 Dec. 2016), pp.273-282, 10 p.
Publisher
University of Kufa Faculty of Science Department of live Sciences
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract EN
The interplay between Th-17 and Th-22 cells plays vital role in tumor immunity .
Therefore, this study aimed to focus on these cells in patients with breast cancer.
The results of this study showed that there were a highly significant increment in concentrations of IL-17A(139.5±17pg/ml) compared with control group which was (41.33±11.3pg/ml) and showed results were a highly significant elevation in concentration of IL-23P19 (192.73±22.3pg/ml) while control group was (121.41±14.7pg/ml).
Also The results showed a highly significant increment in concentration of IL-22 (137.25±24.6pg/ml) compared to control group which was (77.67±13.7pg/ml) and also in TNF-α concentration was (200±23.7pg/ml) compared with control group which was (10.5±7.3pg/ml).
Molecular findings recorded a significant elevation in the levels of AP-1 gene expression were Fos 18.76±7.8 in patients group and 9.05±1.12 control group, also the values of JunD gene 15.77±9.43 and 6.18±0.112, and lastly JunB 23.223±11.34 in comparison to control group7.33±3.76.Overall findings revealed considerable inflammatory response by Th-17 and Th-22 and remarkable AP-1 gene expression
American Psychological Association (APA)
al-Khafaf, Dina M. R.& al-Umari, Raghdah S. M.& al-Khuzai, Ziyad Mutib Fajh. 2016. Evaluation of T-helper 22 and T-helper 17 in patients with breast cancer. al-Kufa University Journal for Biology،Vol. 8, no. 3, pp.273-282.
https://search.emarefa.net/detail/BIM-747303
Modern Language Association (MLA)
al-Khafaf, Dina M. R.…[et al.]. Evaluation of T-helper 22 and T-helper 17 in patients with breast cancer. al-Kufa University Journal for Biology Vol. 8, no. 3 (2016), pp.273-282.
https://search.emarefa.net/detail/BIM-747303
American Medical Association (AMA)
al-Khafaf, Dina M. R.& al-Umari, Raghdah S. M.& al-Khuzai, Ziyad Mutib Fajh. Evaluation of T-helper 22 and T-helper 17 in patients with breast cancer. al-Kufa University Journal for Biology. 2016. Vol. 8, no. 3, pp.273-282.
https://search.emarefa.net/detail/BIM-747303
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 280-282
Record ID
BIM-747303