Hepatitis C in children with chronic kidney disease : a single-center, Egypt
Joint Authors
Adham, Tamir
Abduh, Hana
al-Akhras, Ahmad
Mahmud, Abd al-Nasir Husayn
Yusuf, Dua Muhammad
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 1 (28 Feb. 2017), pp.102-106, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Prevalence of hepatitis C varies largely according to geographical distribution, and Egypt so far has the highest prevalence worldwide.
The aim of this study was to evaluate hepatitis C infection in chronic kidney disease (CKD) children in our center with regard to its incidence and other morbidities.
This is a cross-sectional study involving 50 children with CKD, not on dialysis.
All patients underwent a thorough history taking including disease duration and mean duration of admission, clinical examination including blood pressure measurements, and routine laboratory examination such as hemoglobin level, serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, and creatinine.
The detection of anti-hepatitis C virus (HCV) antibodies was done in all patients based on the use of third-generation enzyme immunoassay (EIA) that detects antibodies directed against various HCV epitopes.
Nine (18%) children were found to be hepatitis C positive and 41 were negative to hepatitis C.
Infected cases were of older age group and had a longer duration of CKD, lower estimated glomerular filtration rate (eGFR), lower hemoglobin, higher ALT, higher serum urea, and creatinine.
We conclude that 18% of children with CKDs have hepatitis C infection, and those with longer the duration of renal disease is more likely to be positive for HCV.
Furthermore, HCV infection may predispose to higher deterioration of eGFR, lower hemoglobin level, and more days of admission.
We recommend routine testing of HCV in all children with CKD
American Psychological Association (APA)
Yusuf, Dua Muhammad& Abduh, Hana& al-Akhras, Ahmad& Adham, Tamir& Mahmud, Abd al-Nasir Husayn. 2017. Hepatitis C in children with chronic kidney disease : a single-center, Egypt. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 1, pp.102-106.
https://search.emarefa.net/detail/BIM-748877
Modern Language Association (MLA)
Yusuf, Dua Muhammad…[et al.]. Hepatitis C in children with chronic kidney disease : a single-center, Egypt. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 1 (Jan. / Feb. 2017), pp.102-106.
https://search.emarefa.net/detail/BIM-748877
American Medical Association (AMA)
Yusuf, Dua Muhammad& Abduh, Hana& al-Akhras, Ahmad& Adham, Tamir& Mahmud, Abd al-Nasir Husayn. Hepatitis C in children with chronic kidney disease : a single-center, Egypt. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 1, pp.102-106.
https://search.emarefa.net/detail/BIM-748877
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 106
Record ID
BIM-748877