Membranous glomerulopathy and massive cervical lymphadenopathy due to immunoglobulin G4-disease
Joint Authors
al-Rashid, Kamal
al-Badr, Shaykhah
Madda, John
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 1 (28 Feb. 2017), pp.149-153, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
A 32-year-old male presented with acute and severe nephrotic syndrome as well as massive right cervical lymphadenopathy for <2 years.
Computed tomography scan of the chest, abdomen, and pelvis did not reveal any lymphadenopathy.
Histopathology and immunohistochemical testing of his lymph node biopsy showed infiltrate enriched with immunoglobulin G4 (IgG4)-positive plasma cells.
His kidney biopsy showed granular membranous deposits of IgG4 in the basement membrane without interstitial infiltrate.
Antiphospholipid 2 receptor antibodies were absent excluding its “idiopathic” nature.
Since he was allergic to rituximab, he was treated with corticosteroids for two months and a combination of tacrolimus and mycophenolate.
His lymphadenopathy disappeared, and his proteinuria abated.
The dose of the latter two medications was reduced to half after four months and will be maintained for a minimum of two years to prevent relapse of his disease.
American Psychological Association (APA)
al-Rashid, Kamal& al-Badr, Shaykhah& Madda, John. 2017. Membranous glomerulopathy and massive cervical lymphadenopathy due to immunoglobulin G4-disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 1, pp.149-153.
https://search.emarefa.net/detail/BIM-748895
Modern Language Association (MLA)
al-Rashid, Kamal…[et al.]. Membranous glomerulopathy and massive cervical lymphadenopathy due to immunoglobulin G4-disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 1 (Jan. / Feb. 2017), pp.149-153.
https://search.emarefa.net/detail/BIM-748895
American Medical Association (AMA)
al-Rashid, Kamal& al-Badr, Shaykhah& Madda, John. Membranous glomerulopathy and massive cervical lymphadenopathy due to immunoglobulin G4-disease. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 1, pp.149-153.
https://search.emarefa.net/detail/BIM-748895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 152-153
Record ID
BIM-748895