Effectiveness of zinc supplementation in regulating serum hormonal and inflammatory status in hypothyroidism patients

Abstract EN

This study was designed to investigate the serum level of thyroid-stimulating hormone,thyroxine, triiodothyronine, interleukin-6 and tumour necrosis factor-α” in hypothyroidism patients, and to reveal their relationship with serum zinc level in 27 patients with hypothyroidism, and 27 control group.

The results disclosed that serum zinc, interleukin-6 and tumour necrosis factor-α levelsin hypothyroidism patients are significantly lower (p˂0.05) than the control group.

While serum thyroid stimulating hormone level, was significantly higher in hypothyroidism patients than the control (p˂0.05).

After zinc administration, the patients group showeda significant increase in “interleukin-6 and tumour necrosis factor-α” level (p˂0.05) in comparison with control group.