Rhinocerebral mucormycosis : a review of 32 cases in Mosul

Abstract EN

The aim of the present study is to evaluate the effectiveness of oral systemic antifungal (fluconazol) with nasal antifungal wash and aggressive surgical debridement in treatment of rhinocerebral mucormycosis.

In a prospective hospital based study, we reviewed the management of 32 patients with rhinocerebral mucormycosis in Mosul general hospital and Al-Rahma Hospital (Mosul_Iraq), over a period of 7 years (Jan 1995 - Dec 2001).

Diabetes mellitus was the main underlying cause in our patients and the main causative agent was mucor sp..The mortality rate was 56.2%.

In Conclusion management of patients with rhinocerebral mucormycosis by oral antifungal (fluconazol) with nasal antifungal wash by mixture of clotrimazol and 20% sodium bicarbonate solution and aggressive surgical debridement after the control of the underlying disease, seems to be effective