Molecular classification of Iraqi breast cancer patients and its correlation with patients’ profile
Joint Authors
al-Naqqash, Manwar A.
Jasim, Mustafa K.
al-Rawaq, Khudayr J.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 58, Issue 3 (30 Sep. 2016), pp.197-201, 5 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2016-09-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Abstract EN
Background : Breast cancer is a complex, multifaceted disease encompassing a great variety of entities that show considerable variation in clinical, morphological and molecular attributes.
Objective : The aim of this study to evaluate patients’ molecular profile (Estrogen receptor, Progesterone receptor, HER2/neu and Ki-67).
Patients & Methods: This is a cross-sectional descriptive study was done in Baghdad oncology teaching hospital from December 2015 to April 2016, carried on 100 breast cancer female patients with their age range from 27 to 73 years old and with their histopathology reports and (IHC) results.
Results : The highest incidence of breast cancer among patients in 5th (40-49 years) and 6th (50-59 years) decades of life both groups are (32%), estrogen and progesterone values were observed (74% and 75% respectively) and 69 patients (69%) with Ki-67 ≥14.
Conclusions : Most of the breast cancer patients in the current study were estrogen and progesterone (Hormonal) positive, and Luminal B-like was the most common molecular subtype (53%) due to high Ki-67 index.
There was a strong correlation between estrogen and progesterone in the studied patients with highly significant P value <0.0001
American Psychological Association (APA)
al-Rawaq, Khudayr J.& al-Naqqash, Manwar A.& Jasim, Mustafa K.. 2016. Molecular classification of Iraqi breast cancer patients and its correlation with patients’ profile. Journal of the Faculty of Medicine Baghdad،Vol. 58, no. 3, pp.197-201.
https://search.emarefa.net/detail/BIM-752933
Modern Language Association (MLA)
al-Rawaq, Khudayr J.…[et al.]. Molecular classification of Iraqi breast cancer patients and its correlation with patients’ profile. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 3 (2016), pp.197-201.
https://search.emarefa.net/detail/BIM-752933
American Medical Association (AMA)
al-Rawaq, Khudayr J.& al-Naqqash, Manwar A.& Jasim, Mustafa K.. Molecular classification of Iraqi breast cancer patients and its correlation with patients’ profile. Journal of the Faculty of Medicine Baghdad. 2016. Vol. 58, no. 3, pp.197-201.
https://search.emarefa.net/detail/BIM-752933
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 200-201
Record ID
BIM-752933