Immunostimulant activity of levamisole to polyvalent FMD vaccine in buffaloes
Other Title(s)
تأثير الليفاميزول كمحسن مناعي علي لقاح الحمي القلاعية المتعدد في الجاموس
Joint Authors
al-Shahidi, M. S.
Abd al-Fattah, Shairah A.
Jamal, M. G.
Salim, S. A.
Source
Suez Canal Veterinary Medicine Journal
Issue
Vol. 20, Issue 2 (31 Dec. 2015), pp.449-461, 13 p.
Publisher
Suez Canal University Faculty of Veterinary Medicine
Publication Date
2015-12-31
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
In Egypt, many challenges facing eradication strategy of FMD concerning the short term immunity induced by inactivated polyvalent FMD vaccine.
The aim of the study was directed to ascertain whether post vaccination antibodies against FMDV in buffaloes could be enhanced by administration with levamisole.
To achieve the goal, 24 buffaloes were divided into 4 groups, G1 is non vaccinated non adjuvanted group, G2 is vaccine control group, G3 is simultaneously FMD vaccinated and levamisole stimulated group and G4 is FMD vaccinated 7 days after levamisole stimulation.
Blood samples were examined for 16 succesive weeks post vaccination for FMD antibodies to serotypes O, A and SAT-2 by ELISA test.
The results revealed that animalssimultinously vaccinated and treated with levamisole was higher than the group adjuvinated with levamisole 7 days before FMD vaccination.
Levamisole has stimulant effect on the vaccinalimmunity of buffaloes to FMD serotypes O, A and SAT2.
Antibody titers of FMD in animal groups were parallel in each group with a high titer in serotype A than O and SAT2.
Further investigations are needed to explore the effect of levamisole on cell mediated immune response and challenge test in buffaloes
American Psychological Association (APA)
al-Shahidi, M. S.& Abd al-Fattah, Shairah A.& Salim, S. A.& Jamal, M. G.. 2015. Immunostimulant activity of levamisole to polyvalent FMD vaccine in buffaloes. Suez Canal Veterinary Medicine Journal،Vol. 20, no. 2, pp.449-461.
https://search.emarefa.net/detail/BIM-754168
Modern Language Association (MLA)
Abd al-Fattah, Shairah A.…[et al.]. Immunostimulant activity of levamisole to polyvalent FMD vaccine in buffaloes. Suez Canal Veterinary Medicine Journal Vol. 20, no. 2 (2015), pp.449-461.
https://search.emarefa.net/detail/BIM-754168
American Medical Association (AMA)
al-Shahidi, M. S.& Abd al-Fattah, Shairah A.& Salim, S. A.& Jamal, M. G.. Immunostimulant activity of levamisole to polyvalent FMD vaccine in buffaloes. Suez Canal Veterinary Medicine Journal. 2015. Vol. 20, no. 2, pp.449-461.
https://search.emarefa.net/detail/BIM-754168
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 458-461
Record ID
BIM-754168